Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype
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AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesisChromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleationThe tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lensIdentification of pax6-dependent gene regulatory networks in the mouse lens.Ocular manifestations of branchio-oculo-facial syndrome: report of a novel mutation and review of the literature.Disruption of mouse corneal epithelial differentiation by conditional inactivation of pnn.p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis.Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage.Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulatorsThe cellular and molecular mechanisms of vertebrate lens development.Molecular characterization of mouse lens epithelial cell lines and their suitability to study RNA granules and cataract associated genesWhole exome sequence analysis of Peters anomaly.The functional role of the Meis/Prep-binding elements in Pax6 locus during pancreas and eye developmentLoss of Msx2 function down-regulates the FoxE3 expression and results in anterior segment dysgenesis resembling Peters anomaly.The endocytic recycling regulatory protein EHD1 Is required for ocular lens developmentAP-2β Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development.Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina.Analysis of TFAP2A mutations in Branchio-Oculo-Facial Syndrome indicates functional complexity within the AP-2α DNA-binding domainConditional deletion of AP-2β in mouse cranial neural crest results in anterior segment dysgenesis and early-onset glaucoma.Sfrp1 and Sfrp2 are not involved in Wnt/β-catenin signal silencing during lens induction but are required for maintenance of Wnt/β-catenin signaling in lens epithelial cells.Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development.Epigenetic regulatory mechanisms in vertebrate eye development and disease.Building the developmental oculome: systems biology in vertebrate eye development and disease.The lens equator: a platform for molecular machinery that regulates the switch from cell proliferation to differentiation in the vertebrate lens.Systems biology of lens development: A paradigm for disease gene discovery in the eye.Derivation of multiple cranial tissues and isolation of lens epithelium-like cells from human embryonic stem cells.Deficiency of the RNA binding protein caprin2 causes lens defects and features of Peters anomaly.Generation of a new mouse model of glaucoma characterized by reduced expression of the AP-2β and AP-2δ proteins.Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survivalRegulation of mouse lens maturation and gene expression by Krüppel-like factor 4Pax6 is essential for lens fiber cell differentiation.Signaling and Gene Regulatory Networks in Mammalian Lens Development.AP-2ε Expression in Developing Retina: Contributing to the Molecular Diversity of Amacrine Cells.AP-2α is required after lens vesicle formation to maintain lens integrity.Conditional Deletion of AP-2α and AP-2β in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function.
P2860
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P2860
Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype
description
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im März 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/03/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/03/01)
@nl
наукова стаття, опублікована в березні 2008
@uk
مقالة علمية (نشرت في مارس 2008)
@ar
name
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@ast
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@en
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@nl
type
label
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@ast
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@en
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@nl
prefLabel
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@ast
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@en
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@nl
P2093
P2860
P356
P1476
Cell autonomous roles for AP-2 ...... lens epithelial cell phenotype
@en
P2093
Giuseppe F. Pontoriero
Jiri Zavadil
Judith A. West-Mays
Paula Deschamps
Shelley Sullivan
Trevor Williams
P2860
P304
P356
10.1002/DVDY.21445
P577
2008-03-01T00:00:00Z