The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency.
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DOCK8 deficiency impairs CD8 T cell survival and function in humans and miceLytic immune synapse function requires filamentous actin deconstruction by Coronin 1AConstitutive turnover of phosphorylation at Thr-412 of human p57/coronin-1 regulates the interaction with actinCombined immunodeficiency associated with DOCK8 mutationsCyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitisT Lymphocyte Migration: An Action Movie Starring the Actin and Associated Actors.T Cell Adolescence: Maturation Events Beyond Positive SelectionCell biological steps and checkpoints in accessing NK cell cytotoxicityThe multiple faces of leukocyte interstitial migrationThe actin-bundling protein L-plastin supports T-cell motility and activationStriking the Right Balance Determines TB or Not TBCoronin-1A: immune deficiency in humans and miceActin cytoskeletal defects in immunodeficiencyMolecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseCoronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signalingGenetics of SCIDMechanism of a concentration-dependent switch between activation and inhibition of Arp2/3 complex by coroninActivation of the cAMP/protein kinase A signalling pathway by coronin 1 is regulated by cyclin-dependent kinase 5 activityT-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrowEmergent Role of Coronin-1a in Neuronal Signaling.Proteome of acidic phospholipid-binding proteins: spatial and temporal regulation of Coronin 1A by phosphoinositidesThe actin-bundling protein L-plastin dissociates CCR7 proximal signaling from CCR7-induced motilityTwo-photon microscopy analysis of leukocyte trafficking and motility.Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA-regulated adhesions.Cryo-EM reveals different coronin binding modes for ADP- and ADP-BeFx actin filamentsThe disease-linked Glu-26-Lys mutant version of Coronin 1A exhibits pleiotropic and pathway-specific signaling defects.Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome.Dissecting mammalian immunity through mutation.Altered T-cell entry and egress in the absence of Coronin 1A attenuates murine acute graft versus host disease.Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes.Porcine coronin 1A contributes to nuclear factor-kappa B (NF-κB) inactivation during Haemophilus parasuis infection.Mast cell function is not altered by Coronin-1A deficiency.Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies.Gene expression profiles associated with aging and mortality in humans.Personalized medicine for gliomasDifferential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b.Compound heterozygous CORO1A mutations in siblings with a mucocutaneous-immunodeficiency syndrome of epidermodysplasia verruciformis-HPV, molluscum contagiosum and granulomatous tuberculoid leprosy.β-Actin specifically controls cell growth, migration, and the G-actin poolMicroenvironmental Control of High-Speed Interstitial T Cell Migration in the Lymph Node.Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation.
P2860
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P248
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P2860
The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The actin regulator coronin 1A ...... vere combined immunodeficiency
@nl
The actin regulator coronin 1A ...... ere combined immunodeficiency.
@ast
The actin regulator coronin 1A ...... ere combined immunodeficiency.
@en
type
label
The actin regulator coronin 1A ...... vere combined immunodeficiency
@nl
The actin regulator coronin 1A ...... ere combined immunodeficiency.
@ast
The actin regulator coronin 1A ...... ere combined immunodeficiency.
@en
prefLabel
The actin regulator coronin 1A ...... vere combined immunodeficiency
@nl
The actin regulator coronin 1A ...... ere combined immunodeficiency.
@ast
The actin regulator coronin 1A ...... ere combined immunodeficiency.
@en
P2093
P2860
P921
P3181
P356
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P1476
The actin regulator coronin 1A ...... ere combined immunodeficiency.
@en
P2093
Christopher C Goodnow
Craig N Jenne
David W Roadcap
Irina L Grigorova
James E Bear
Jason G Cyster
Jennifer M Puck
Jinping An
Kenneth Paris
Lawrence R Shiow
P2860
P2888
P304
P3181
P356
10.1038/NI.1662
P407
P577
2008-10-05T00:00:00Z
P5875
P6179
1028044442