beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
about
Arrestins: ubiquitous regulators of cellular signaling pathwaysG protein-coupled receptor kinase 2 promotes flaviviridae entry and replicationDesensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interferenceBeta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expressionNedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptorDosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCRAgonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivoInternational Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) familyBeta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transductionThe structural basis of arrestin-mediated regulation of G-protein-coupled receptorsAnalyzing the roles of multi-functional proteins in cells: The case of arrestins and GRKsNegative regulation of the novel norpA(P24) suppressor, diehard4, in the endo-lysosomal trafficking underlies photoreceptor cell degenerationCrystal Structure of Arrestin-3 Reveals the Basis of the Difference in Receptor Binding Between Two Non-visual SubtypesHomo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation controlRole of the proline-rich domain of dynamin-2 and its interactions with Src homology 3 domains during endocytosis of the AT1 angiotensin receptorSignaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4β-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel.beta-Arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2.The type III TGFβ receptor regulates filopodia formation via a Cdc42-mediated IRSp53-N-WASP interaction in epithelial cells.Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis.Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arraysA nonsense mutation in S-antigen (p.Glu306*) causes Oguchi disease.Determinants Present in the Receptor Carboxy Tail Are Responsible for Differences in Subtype-Specific Coupling of beta-Adrenergic Receptors to Phosphoinositide 3-Kinase.Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR)Regulation of GPR54 signaling by GRK2 and {beta}-arrestinBeta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2.GPR54 regulates ERK1/2 activity and hypothalamic gene expression in a Gα(q/11) and β-arrestin-dependent manner.β2-Adrenoceptor involved in smoking-induced airway mucus hypersecretion through β-arrestin-dependent signaling.D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model.Beyond desensitization: physiological relevance of arrestin-dependent signaling.Distinct and shared roles of β-arrestin-1 and β-arrestin-2 on the regulation of C3a receptor signaling in human mast cells.Genetic evidence for a mammalian retromer complex containing sorting nexins 1 and 2.The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activationTricyclic antidepressants exhibit variable pharmacological profiles at the α(2A) adrenergic receptor.Molecular basis of lysophosphatidic acid-induced NF-κB activationbeta-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6.Nedd4-1 and beta-arrestin-1 are key regulators of Na+/H+ exchanger 1 ubiquitylation, endocytosis, and functionBeta -Arrestin 1 down-regulation after insulin treatment is associated with supersensitization of beta 2 adrenergic receptor Galpha s signaling in 3T3-L1 adipocytes.
P2860
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P2860
beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
description
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2001
@ast
im Februar 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/02/13)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/02/13)
@nl
наукова стаття, опублікована в лютому 2001
@uk
name
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@ast
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@en
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@nl
type
label
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@ast
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@en
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@nl
prefLabel
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@ast
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@en
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@nl
P2093
P2860
P3181
P356
P1476
beta-Arrestin 1 and 2 differen ...... ptor signaling and trafficking
@en
P2093
D. A. Conner
R. J. Lefkowitz
S. J. Perry
T. A. Kohout
P2860
P304
P3181
P356
10.1073/PNAS.041608198
P407
P577
2001-02-13T00:00:00Z