Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart.
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Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]Slug is a direct Notch target required for initiation of cardiac cushion cellularizationCharacterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract developmentTargeting BMP signalling in cardiovascular disease and anaemiaEndocardial and epicardial epithelial to mesenchymal transitions in heart development and diseaseKrüppel-like factor 2 is required for normal mouse cardiac developmentSignaling via the Tgf-beta type I receptor Alk5 in heart developmentAbcc6 deficiency causes increased infarct size and apoptosis in a mouse cardiac ischemia-reperfusion modelMurine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract developmentTransforming growth factor Beta2 is required for valve remodeling during heart developmentBMP type II receptor regulates positioning of outflow tract and remodeling of atrioventricular cushion during cardiogenesisBMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesisLigand-specific function of transforming growth factor beta in epithelial-mesenchymal transition in heart developmentImpairment of endothelial-mesenchymal transformation during atrioventricular cushion formation in Tmem100 null embryosMsx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardiumScleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivoMatrix metalloproteinase 2-integrin alpha(v)beta3 binding is required for mesenchymal cell invasive activity but not epithelial locomotion: a computational time-lapse study.Role of extracellular matrix signaling cues in modulating cell fate commitment for cardiovascular tissue engineeringAcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development.Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis.Myocardial deletion of Smad4 using a novel α skeletal muscle actin Cre recombinase transgenic mouse causes misalignment of the cardiac outflow tractProgesterone receptor activates Msx2 expression by downregulating TNAP/Akp2 and activating the Bmp pathway in EpH4 mouse mammary epithelial cells.VEGF signaling has distinct spatiotemporal roles during heart valve development.Deficient signaling via Alk2 (Acvr1) leads to bicuspid aortic valve development.Cell autonomous requirement of endocardial Smad4 during atrioventricular cushion development in mouse embryosThe role of the 3'UTR region in the regulation of the ACVR1/Alk-2 gene expression.Bone Morphogenetic Protein (BMP) signaling in development and human diseasesDynamic analysis of BMP-responsive smad activity in live zebrafish embryosBMP-2 induces versican and hyaluronan that contribute to post-EMT AV cushion cell migration.The essential autophagy gene ATG7 modulates organ fibrosis via regulation of endothelial-to-mesenchymal transition.Inactivation of Bmp4 from the Tbx1 expression domain causes abnormal pharyngeal arch artery and cardiac outflow tract remodeling.BMP-2 and TGFβ2 shared pathways regulate endocardial cell transformation.ALK1 as an emerging target for antiangiogenic therapy of cancerLoss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1.Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development.Conversion of vascular endothelial cells into multipotent stem-like cells.Myocardium and BMP signaling are required for endocardial differentiationBMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks.Endothelial-mesenchymal transition and its contribution to the emergence of stem cell phenotype
P2860
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P2860
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart
@nl
Atrioventricular cushion trans ...... in the developing mouse heart.
@ast
Atrioventricular cushion trans ...... in the developing mouse heart.
@en
type
label
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart
@nl
Atrioventricular cushion trans ...... in the developing mouse heart.
@ast
Atrioventricular cushion trans ...... in the developing mouse heart.
@en
prefLabel
Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart
@nl
Atrioventricular cushion trans ...... in the developing mouse heart.
@ast
Atrioventricular cushion trans ...... in the developing mouse heart.
@en
P2093
P2860
P3181
P1476
Atrioventricular cushion trans ...... in the developing mouse heart.
@en
P2093
Andre Nagy
Jikui Wang
Jonathan A Epstein
Marek Dudas
Michael D Schneider
Penny Thomas
Somyoth Sridurongrit
Vesa Kaartinen
P2860
P304
P3181
P356
10.1016/J.YDBIO.2005.07.035
P407
P577
2005-10-01T00:00:00Z