Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25
about
The Mediator complex and transcription regulationThe transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossificationTranscription factors Sox10 and Sox2 functionally interact with positive transcription elongation factor b in Schwann cells.A design principle underlying the paradoxical roles of E3 ubiquitin ligasesAn Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine EmbryosMediator and human diseaseComparison of IRES and F2A-based locus-specific multicistronic expression in stable mouse lines.SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters.Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesisMicroRNAs in cartilage development, homeostasis, and disease.In vivo genome-wide analysis of multiple tissues identifies gene regulatory networks, novel functions and downstream regulatory genes for Bapx1 and its co-regulation with Sox9 in the mammalian vertebral column.Palatogenesis: morphogenetic and molecular mechanisms of secondary palate developmentCRYPTIC PRECOCIOUS/MED12 is a novel flowering regulator with multiple target steps in ArabidopsisThe postnatal role of Sox9 in cartilage.Zebrafish Craniofacial Development: A Window into Early PatterningE3 ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation.E6-AP/UBE3A protein acts as a ubiquitin ligase toward SOX9 protein.SOX9: a stem cell transcriptional regulator of secreted niche signaling factors.Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells.A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development.MicroRNAs in Palatogenesis and Cleft Palate.Unraveling the transcriptional regulatory machinery in chondrogenesis.How ubiquitination regulates the TGF-β signalling pathway: new insights and new players: new isoforms of ubiquitin-activating enzymes in the E1-E3 families join the game.Macro view of microRNA function in osteoarthritis.microRNAs and cartilage.Crosstalk between kinases and Nedd4 family ubiquitin ligases.ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain.The E3 ubiquitin ligase WWP2 facilitates RUNX2 protein transactivation in a mono-ubiquitination manner during osteogenic differentiation.A Novel Regulatory Mechanism of Type II Collagen Expression via a SOX9-dependent Enhancer in Intron 6.Silencing of WWP2 inhibits adhesion, invasion, and migration in liver cancer cells.SOX9 and the many facets of its regulation in the chondrocyte lineage.Homozygous MED25 mutation implicated in eye-intellectual disability syndrome.The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group membersTranscriptional Network Controlling Endochondral Ossification.Modeling digits. Digit patterning is controlled by a Bmp-Sox9-Wnt Turing network modulated by morphogen gradients.WWP2 ubiquitin ligase and its isoforms: new biological insight and promising disease targets.Homozygous missense mutation in MED25 segregates with syndromic intellectual disability in a large consanguineous family.Regulation of Cartilage Development and Diseases by Transcription Factors.Paip1, an effective stimulator of translation initiation, is targeted by WWP2 for ubiquitination and degradation
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P248
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P2860
Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25
description
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans Nature Communications
@fr
artículu científicu espublizáu en 2011
@ast
scientific journal article
@en
vedecký článok (publikovaný 2011/01/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/01/01)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в січні 2011
@uk
name
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@ast
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@en
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@nl
type
label
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@ast
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@en
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@nl
prefLabel
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@ast
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@en
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@nl
P2093
P2860
P921
P356
P1476
Wwp2 is essential for palatoge ...... n Sox9 and mediator subunit 25
@en
P2093
Benoit de Crombrugghe
Haruhiko Akiyama
Hiroki Murao
Jian Min Deng
John H Postlethwait
Koji Yamamoto
Matthew L Warman
Richard R Behringer
Takashi Nakamura
Tsunemitsu Soeda
P2860
P2888
P356
10.1038/NCOMMS1242
P407
P577
2011-01-01T00:00:00Z
P6179
1003938677