Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry
about
The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acidsCEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the ciliumCSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish developmentMultivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases.The chemical complexity of cellular microtubules: tubulin post-translational modification enzymes and their roles in tuning microtubule functionsLoss of SPEF2 function in mice results in spermatogenesis defects and primary ciliary dyskinesiaCiliary/Flagellar Protein UbiquitinationThe IN/OUT assay: a new tool to study ciliogenesisMechanical Stimulation by Postnasal Drip Evokes CoughIdentification of tubulin deglutamylase among Caenorhabditis elegans and mammalian cytosolic carboxypeptidases (CCPs)Disruption of Ttll5/stamp gene (tubulin tyrosine ligase-like protein 5/SRC-1 and TIF2-associated modulatory protein gene) in male mice causes sperm malformation and infertilityTubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal ciliaBiallelic variants in TTLL5, encoding a tubulin glutamylase, cause retinal dystrophyTubulin tyrosine ligase-like genes ttll3 and ttll6 maintain zebrafish cilia structure and motility.hemingway is required for sperm flagella assembly and ciliary motility in Drosophila.Kinesin-13 regulates the quantity and quality of tubulin inside cilia.The nexin link and B-tubule glutamylation maintain the alignment of outer doublets in the ciliary axoneme.Cytoplasmic carboxypeptidase 5 regulates tubulin glutamylation and zebrafish cilia formation and functionThe tubulin code: molecular components, readout mechanisms, and functionsPost-translational modifications of microtubules.Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions.Tubulin acetylation: responsible enzymes, biological functions and human diseases.Quantitative peptidomics of Purkinje cell degeneration miceMicrofluidic characterization of cilia-driven fluid flow using optical coherence tomography-based particle tracking velocimetry.Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo.A NIMA-Related Kinase Suppresses the Flagellar Instability Associated with the Loss of Multiple Axonemal Structures.Family-Based Association Study of Pulmonary Function in a Population in Northeast Asia.Cytosolic carboxypeptidase 1 is involved in processing α- and β-tubulinTubulin-dynein system in flagellar and ciliary movementThe evolutionary significance of depression in Pathogen Host Defense (PATHOS-D).Summary of papers presented at the 2012 seventh international cough symposiumLoss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutationsCaenorhabditis elegans glutamylating enzymes function redundantly in male mating.A conserved flagella-associated protein in Chlamydomonas, FAP234, is essential for axonemal localization of tubulin polyglutamylase TTLL9.Cilia in the nervous system: linking cilia function and neurodevelopmental disorders.Sperm flagella: comparative and phylogenetic perspectives of protein components.Primary ciliary dyskinesia: recent advances in epidemiology, diagnosis, management and relationship with the expanding spectrum of ciliopathy.Riding the wave of ependymal cilia: genetic susceptibility to hydrocephalus in primary ciliary dyskinesia.Microtubule defects & Neurodegeneration.Multiciliated cells
P2860
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P2860
Tubulin polyglutamylation is essential for airway ciliary function through the regulation of beating asymmetry
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@ast
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@en
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@nl
type
label
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@ast
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@en
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@nl
prefLabel
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@ast
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@en
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@nl
P2093
P2860
P3181
P356
P1476
Tubulin polyglutamylation is e ...... egulation of beating asymmetry
@en
P2093
Kenji Nakamura
Koji Ikegami
Lawrence E Ostrowski
Mitsutoshi Setou
Showbu Sato
P2860
P304
10490-10495
P3181
P356
10.1073/PNAS.1002128107
P407
P577
2010-05-24T00:00:00Z