COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast
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COP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phaseThe subunit CSN6 of the COP9 signalosome is cleaved during apoptosisERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer DevelopmentMultiple functions of Jab1 are required for early embryonic development and growth potential in micePenetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alikeThe Evolution of COP9 Signalosome in Unicellular and Multicellular OrganismsFunction of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradationDownregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stabilityDual regulation of dendritic morphogenesis in Drosophila by the COP9 signalosome.COP9 limits dendritic branching via Cullin3-dependent degradation of the actin-crosslinking BTB-domain protein Kelch.Role of individual subunits of the Neurospora crassa CSN complex in regulation of deneddylation and stability of cullin proteins.Knockdown of COPS3 Inhibits Lung Cancer Tumor Growth in Nude Mice by Blocking Cell Cycle Progression.Nedd8 on cullin: building an expressway to protein destruction.Refined mapping of a quantitative trait locus on chromosome 1 responsible for mouse embryonic death.Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice.Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization.Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.Revisiting the COP9 signalosome as a transcriptional regulator.Neddylation and deneddylation in cardiac biologyCharacterization of the role of COP9 signalosome in regulating cullin E3 ubiquitin ligase activityThe COP9 signalosome and cullin-RING ligases in the heartThe COP9 signalosome and vascular function: intriguing possibilities?The COP9 signalosome is vital for timely repair of DNA double-strand breaks.CSN6 deregulation impairs genome integrity in a COP1-dependent pathwayEssential roles of Jab1 in cell survival, spontaneous DNA damage and DNA repairKnockdown of subunit 3 of the COP9 signalosome inhibits C2C12 myoblast differentiation via NF-KappaB signaling pathwayCOP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer.THE COP9 SIGNALOSOME, A NOVEL, ESSENTIAL REGULATOR OF SKELETAL DEVELOPMENT AND TUMORIGENESIS.Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development.CSN5 specifically interacts with CDK2 and controls senescence in a cytoplasmic cyclin E-mediated manner.Mouse chromosome engineering for modeling human disease.CSN6 positively regulates c-Jun in a MEKK1-dependent manner.Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing TranscriptionGenomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression.COP9 signalosome function in the DDR.Roles of COP9 signalosome in cancer.Inhibition of Csn3 expression induces growth arrest and apoptosis of hepatocellular carcinoma cells.COP9 signalosome subunit 8 is required for postnatal hepatocyte survival and effective proliferation.Depletion of Jab1 inhibits proliferation of pancreatic cancer cell lines.The COP9 signalosome regulates Skp2 levels and proliferation of human cells.
P2860
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P2860
COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast
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2003 nî lūn-bûn
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2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
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2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
@ast
COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
@en
COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
@nl
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label
COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
@ast
COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
@en
COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
@nl
prefLabel
COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
@ast
COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
@en
COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
@nl
P2093
P2860
P50
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COP9 signalosome subunit 3 is ...... n the mouse embryonic epiblast
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P2093
Allan Bradley
Hisashi Nakamura
James R Lupski
Monica J Justice
Sandra Carattini-Rivera
P2860
P304
P3181
P356
10.1128/MCB.23.19.6798-6808.2003
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P577
2003-10-01T00:00:00Z