Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation
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Agrin binds BMP2, BMP4 and TGFbeta1Decoding the Matrix: Instructive Roles of Proteoglycan ReceptorsCollagen-derived matricryptins promote inhibitory nerve terminal formation in the developing neocortex.The role of agrin in synaptic development, plasticity and signaling in the central nervous systemAgrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contractionSerine proteases, serine protease inhibitors, and protease-activated receptors: roles in synaptic function and behaviorThe Role of Proteases in Hippocampal Synaptic Plasticity: Putting Together Small Pieces of a Complex Puzzle.Immunoscreening of the extracellular proteome of colorectal cancer cells.Degeneration of neuromuscular junction in age and dystrophy.The process-inducing activity of transmembrane agrin requires follistatin-like domainsA mental retardation gene, motopsin/neurotrypsin/prss12, modulates hippocampal function and social interactionCollagen XIX is expressed by interneurons and contributes to the formation of hippocampal synapses.Agrin expression during synaptogenesis induced by traumatic brain injuryThe genetic basis of non-syndromic intellectual disability: a reviewLRP4 is critical for neuromuscular junction maintenanceInjection of a soluble fragment of neural agrin (NT-1654) considerably improves the muscle pathology caused by the disassembly of the neuromuscular junction.A valid mouse model of AGRIN-associated congenital myasthenic syndrome.Integrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regeneration.C-Terminal Fragment of Agrin (CAF): A Novel Marker for Progression of Kidney Disease in Type 2 Diabetics.The C-Terminal Fragment of Agrin (CAF), a Novel Marker of Renal Function, Is Filtered by the Kidney and Reabsorbed by the Proximal Tubule.ECM receptors in neuronal structure, synaptic plasticity, and behavior.Suppression of agrin-22 production and synaptic dysfunction in Cln1 (-/-) mice.Transmembrane agrin regulates dendritic filopodia and synapse formation in mature hippocampal neuron cultures.Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulationExtracellular matrix molecules, their receptors, and secreted proteases in synaptic plasticity.Casting a net on dendritic spines: the extracellular matrix and its receptors.Extracellular matrix control of dendritic spine and synapse structure and plasticity in adulthood.A Novel Egr-1-Agrin Pathway and Potential Implications for Regulation of Synaptic Physiology and Homeostasis at the Neuromuscular JunctionFunctional Roles of the Interaction of APP and Lipoprotein Receptors.The Reference Intervals for Serum C-Terminal Agrin Fragment in Healthy Individuals and as a Biomarker for Renal Function in Kidney Transplant Recipients.Site specific cleavage mediated by MMPs regulates function of agrin.Building and remodeling synapses.Zymogen activation of neurotrypsin and neurotrypsin-dependent agrin cleavage on the cell surface are enhanced by glycosaminoglycans.Linker proteins restore basement membrane and correct LAMA2-related muscular dystrophy in mice.Engineered agrin attenuates the severity of experimental autoimmune myasthenia gravis.Mental retardation-related protease, motopsin (prss12), binds to the BRICHOS domain of the integral membrane protein 2a.Genetic suppression of agrin reduces mania-like behavior in Na+ , K+ -ATPase α3 mutant mice.Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy.Detection of muscle wasting in patients with chronic heart failure using C-terminal agrin fragment: results from the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF).Shaping Synapses by the Neural Extracellular Matrix.
P2860
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P2860
Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation
description
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im November 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/11/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/11/01)
@nl
наукова стаття, опублікована в листопаді 2007
@uk
مقالة علمية (نشرت في نوفمبر 2007)
@ar
name
Specific cleavage of agrin by ...... e linked to mental retardation
@ast
Specific cleavage of agrin by ...... e linked to mental retardation
@en
Specific cleavage of agrin by ...... e linked to mental retardation
@nl
type
label
Specific cleavage of agrin by ...... e linked to mental retardation
@ast
Specific cleavage of agrin by ...... e linked to mental retardation
@en
Specific cleavage of agrin by ...... e linked to mental retardation
@nl
prefLabel
Specific cleavage of agrin by ...... e linked to mental retardation
@ast
Specific cleavage of agrin by ...... e linked to mental retardation
@en
Specific cleavage of agrin by ...... e linked to mental retardation
@nl
P2093
P3181
P356
P1433
P1476
Specific cleavage of agrin by ...... e linked to mental retardation
@en
P2093
Alexander Stephan
Andreas Zurlinden
Birgit Dreier
Birgit Ledermann
Claudio Gisler
Daniel Lüscher
Jens Wölfel
Peter Sonderegger
Raymond Reif
P304
P3181
P356
10.1096/FJ.07-8800COM
P407
P577
2007-11-01T00:00:00Z