An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
about
Protein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humansLymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factorProx1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fateALK1 signaling regulates early postnatal lymphatic vessel developmentmiR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivoFOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in miceAdrenomedullin signaling is necessary for murine lymphatic vascular development.Lymphatic endothelium: morphological, molecular and functional propertiesUp-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumorsMolecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venulesHeterogeneity in the lymphatic vascular system and its originLymph vessels: the forgotten second circulation in health and diseaseDevelopment of the mammalian lymphatic vasculatureLymphatic fate specification: an ERK-controlled transcriptional programNovel characterization and live imaging of Schlemm's canal expressing Prox-1Restoration of lymphatic function rescues obesity in Prox1-haploinsufficient miceDeciphering Pro-Lymphangiogenic Programs during Mammary Involution and Postpartum Breast CancerSchlemm's canal is a unique vessel with a combination of blood vascular and lymphatic phenotypes that forms by a novel developmental processCanal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activityDosage-dependent requirement for mouse Vezf1 in vascular system developmentVascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturationPCNA interacts with Prox1 and represses its transcriptional activityT1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedemaLymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activityPDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculatureProx1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesisRegulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.NFATc1 regulates lymphatic endothelial developmentLymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesityLymphangiogenesis is required for pancreatic islet inflammation and diabetesMacrophages: An Inflammatory Link Between Angiogenesis and Lymphangiogenesis.Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment.Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascades.Discontinuous LYVE-1 expression in corneal limbal lymphatics: dual function as microvalves and immunological hot spots.Blood flow reprograms lymphatic vessels to blood vesselsLymphatic endothelial progenitors bud from the cardinal vein and intersomitic vessels in mammalian embryos.A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy.The zebrafish prospero homolog prox1 is required for mechanosensory hair cell differentiation and functionality in the lateral line.Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells
P2860
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P2860
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
description
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
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im April 2002 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2002/04/02)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/04/02)
@nl
наукова стаття, опублікована у квітні 2002
@uk
مقالة علمية (نشرت في 2-4-2002)
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name
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@ast
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@en
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@nl
type
label
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@ast
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@en
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@nl
prefLabel
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@ast
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@en
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@nl
P2093
P2860
P3181
P356
P1433
P1476
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype
@en
P2093
David G. Jackson
Gerard Grosveld
Guillermo Oliver
Irina Lagutina
Jeffrey T. Wigle
Michael D. Gunn
Natasha Harvey
P2860
P304
P3181
P356
10.1093/EMBOJ/21.7.1505
P407
P577
2002-04-02T00:00:00Z