Pyruvate kinase deficiency in mice protects against malaria
about
How malaria has affected the human genome and what human genetics can teach us about malariaComplex genetic control of susceptibility to malaria: positional cloning of the Char9 locusThe influence of host genetics on erythrocytes and malaria infection: is there therapeutic potential?Host susceptibility to malaria in human and mice: compatible approaches to identify potential resistant genesGenome wide analysis of inbred mouse lines identifies a locus containing Ppar-gamma as contributing to enhanced malaria survivalGenetics of host response to Leishmania tropica in mice - different control of skin pathology, chemokine reaction, and invasion into spleen and liverA mutation in the Icsbp1 gene causes susceptibility to infection and a chronic myeloid leukemia-like syndrome in BXH-2 miceMissing heritability and strategies for finding the underlying causes of complex diseaseRed Blood Cell Function and Dysfunction: Redox Regulation, Nitric Oxide Metabolism, Anemia.Genetic control of high density lipoprotein-cholesterol in AcB/BcA recombinant congenic strains of mice.Simultaneous host and parasite expression profiling identifies tissue-specific transcriptional programs associated with susceptibility or resistance to experimental cerebral malariaPlasmodium strain determines dendritic cell function essential for survival from malariaMalaria liver stage susceptibility locus identified on mouse chromosome 17 by congenic mapping.Iron- and Hepcidin-Independent Downregulation of the Iron Exporter Ferroportin in Macrophages during Salmonella Infection.Rescue of pyruvate kinase deficiency in mice by gene therapy using the human isoenzymeStrain-specific differences in the genetic control of two closely related mycobacteriaCysteamine, the molecule used to treat cystinosis, potentiates the antimalarial efficacy of artemisinin.Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth.Pyruvate kinase deficiency in sub-Saharan Africa: identification of a highly frequent missense mutation (G829A;Glu277Lys) and association with malaria.Mouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives.HIV pharmacogenomics: closer to personalized therapy?Modulation of Malaria Phenotypes by Pyruvate Kinase (PKLR) Variants in a Thai Population.Single gene effects in mouse models of host: pathogen interactions.Functional analysis of erythrocyte determinants of Plasmodium infectionErythrocyte variants and the nature of their malaria protective effect.Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in miceThe mouse Char10 locus regulates severity of pyruvate kinase deficiency and susceptibility to malaria.Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium.Genetic control of susceptibility to infection with Plasmodium chabaudi chabaudi AS in inbred mouse strains.miR-155 Modifies Inflammation, Endothelial Activation and Blood-Brain Barrier Dysfunction in Cerebral Malaria.Host resistance to malaria: using mouse models to explore the host response.Genetic analysis in mice identifies cysteamine as a novel partner for artemisinin in the treatment of malaria.The role of the red blood cell in host defence against falciparum malaria: an expanding repertoire of evolutionary alterations.Complexity in the host response to Salmonella Typhimurium infection in AcB and BcA recombinant congenic strains.Adenosine monophosphate deaminase 3 activation shortens erythrocyte half-life and provides malaria resistance in mice.Safe and Efficient Gene Therapy for Pyruvate Kinase DeficiencyMapping of a quantitative trait locus controlling susceptibility to Coxsackievirus B3-induced viral hepatitis.Mapping of Char10, a novel malaria susceptibility locus on mouse chromosome 9.Phenotypic expression of pyruvate kinase deficiency and protection against malaria in a mouse model.Genetic diversity in human erythrocyte pyruvate kinase.
P2860
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P2860
Pyruvate kinase deficiency in mice protects against malaria
description
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2003
@ast
im Dezember 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/12/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/12/01)
@nl
наукова стаття, опублікована в грудні 2003
@uk
name
Pyruvate kinase deficiency in mice protects against malaria
@ast
Pyruvate kinase deficiency in mice protects against malaria
@en
Pyruvate kinase deficiency in mice protects against malaria
@nl
type
label
Pyruvate kinase deficiency in mice protects against malaria
@ast
Pyruvate kinase deficiency in mice protects against malaria
@en
Pyruvate kinase deficiency in mice protects against malaria
@nl
prefLabel
Pyruvate kinase deficiency in mice protects against malaria
@ast
Pyruvate kinase deficiency in mice protects against malaria
@en
Pyruvate kinase deficiency in mice protects against malaria
@nl
P2093
P356
P1433
P1476
Pyruvate kinase deficiency in mice protects against malaria
@en
P2093
André Nantel
Anny Fortin
Gundula Min-Oo
Mi-Fong Tam
Philippe Gros
P2888
P304
P356
10.1038/NG1260
P407
P577
2003-12-01T00:00:00Z