GATA4 regulates Sertoli cell function and fertility in adult male mice
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An Ebox element in the proximal Gata4 promoter is required for Gata4 expression in vivoCre-mediated stress affects sirtuin expression levels, peroxisome biogenesis and metabolism, antioxidant and proinflammatory signaling pathwaysTargeted Disruption of ALK Reveals a Potential Role in Hypogonadotropic HypogonadismThe Sertoli cell: one hundred fifty years of beauty and plasticity.Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice.Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system.SirT1 is required in the male germ cell for differentiation and fecundity in miceTransient scrotal hyperthermia induces lipid droplet accumulation and reveals a different ADFP expression pattern between the testes and liver in mice.Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice.Population genomics of the killer whale indicates ecotype evolution in sympatry involving both selection and drift.GATA4 deficiency impairs ovarian function in adult mice.The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans.Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation.Adenomatous polyposis coli (APC) is essential for maintaining the integrity of the seminiferous epithelium.Upstream stimulatory factor induces Nr5a1 and Shbg gene expression during the onset of rat Sertoli cell differentiation.Combined loss of the GATA4 and GATA6 transcription factors in male mice disrupts testicular development and confers adrenal-like function in the testes.GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells.GATA4 is essential for bone mineralization via ERα and TGFβ/BMP pathways.GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice.Notch signaling represses GATA4-induced expression of genes involved in steroid biosynthesisRNA Binding Protein Ptbp2 Is Essential for Male Germ Cell DevelopmentAltered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesisGATA factors in endocrine neoplasiaSubculture of Germ Cell-Derived Colonies with GATA4-Positive Feeder Cells from Neonatal Pig TestesLoss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine signaling.Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells.Genetic causes of spermatogenic failure.Sertoli cells are capable of proliferation into adulthood in the transition region between the seminiferous tubules and the rete testis in Wistar rats.mTOR Regulates Gap Junction Alpha-1 Protein Trafficking in Sertoli Cells and Is Required for the Maintenance of Spermatogenesis in Mice.Incomplete cre-mediated excision leads to phenotypic differences between Stra8-iCre; Mov10l1(lox/lox) and Stra8-iCre; Mov10l1(lox/Δ) mice.Direct Reprogramming of Mouse Fibroblasts toward Leydig-like Cells by Defined Factors.Vitamin A deprivation affects the progression of the spermatogenic wave and initial formation of the blood-testis barrier, resulting in irreversible testicular degeneration in mice.Selective deletion of Smad4 in postnatal germ cells does not affect spermatogenesis or fertility in mice.Genetic factors derived from the MRL/MpJ mouse function to maintain the integrity of spermatogenesis after heat exposure.Toxic metabolites, Sertoli cells and Y chromosome related genes are potentially linked to the reproductive toxicity induced by mequindox.Med12 regulates ovarian steroidogenesis, uterine development and maternal effects in the mammalian egg.Probing GATA factor function in mouse Leydig cells via testicular injection of adenoviral vectors.CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH.
P2860
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P2860
GATA4 regulates Sertoli cell function and fertility in adult male mice
description
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Februar 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/02/10)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/02/10)
@nl
наукова стаття, опублікована в лютому 2011
@uk
مقالة علمية (نشرت في 10-2-2011)
@ar
name
GATA4 regulates Sertoli cell function and fertility in adult male mice
@ast
GATA4 regulates Sertoli cell function and fertility in adult male mice
@en
GATA4 regulates Sertoli cell function and fertility in adult male mice
@nl
type
label
GATA4 regulates Sertoli cell function and fertility in adult male mice
@ast
GATA4 regulates Sertoli cell function and fertility in adult male mice
@en
GATA4 regulates Sertoli cell function and fertility in adult male mice
@nl
prefLabel
GATA4 regulates Sertoli cell function and fertility in adult male mice
@ast
GATA4 regulates Sertoli cell function and fertility in adult male mice
@en
GATA4 regulates Sertoli cell function and fertility in adult male mice
@nl
P2093
P2860
P50
P1476
GATA4 regulates Sertoli cell function and fertility in adult male mice
@en
P2093
David B. Wilson
Erica L. Schoeller
Kelle H. Moley
Malgorzata Bielinska
Rosemarie Euler
P2860
P356
10.1016/J.MCE.2010.12.019
P577
2011-02-10T00:00:00Z