Akt promotes BMP2-mediated osteoblast differentiation and bone development
about
Modulation of osteoblastic/odontoblastic differentiation of adult mesenchymal stem cells through gene introduction: a brief reviewConditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation.Improving treatment strategies for patients with metastatic castrate resistant prostate cancer through personalized computational modeling.Selective signaling by Akt2 promotes bone morphogenetic protein 2-mediated osteoblast differentiation.A recurrent mutation in bone morphogenetic proteins-2-inducible kinase gene is associated with developmental dysplasia of the hip.Calcium Supplement Derived from Gallus gallus domesticus Promotes BMP-2/RUNX2/SMAD5 and Suppresses TRAP/RANK Expression through MAPK Signaling ActivationThe spatiotemporal role of COX-2 in osteogenic and chondrogenic differentiation of periosteum-derived mesenchymal progenitors in fracture repair.Akt- and Erk-mediated regulation of proliferation and differentiation during PDGFRβ-induced MSC self-renewalLow-level laser therapy induces the expressions of BMP-2, osteocalcin, and TGF-β1 in hypoxic-cultured human osteoblasts.Differential effects of STAT proteins on growth hormone-mediated IGF-I gene expression.PTH1 receptor is involved in mediating cellular response to long-chain polyunsaturated fatty acids.Akt activation is required for TGF-β1-induced osteoblast differentiation of MC3T3-E1 pre-osteoblasts.A developmentally inspired combined mechanical and biochemical signaling approach on zonal lineage commitment of mesenchymal stem cells in articular cartilage regenerationEGFR signaling suppresses osteoblast differentiation and inhibits expression of master osteoblastic transcription factors Runx2 and Osterix.Distinct actions of akt1 on skeletal architecture and functionInsulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation.Pannexin 3 functions as an ER Ca(2+) channel, hemichannel, and gap junction to promote osteoblast differentiation.Endothelial cells direct human mesenchymal stem cells for osteo- and chondro-lineage differentiation through endothelin-1 and AKT signaling.Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in miceSelective signaling by Akt1 controls osteoblast differentiation and osteoblast-mediated osteoclast development.mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway.The Effects of the Endocannabinoids Anandamide and 2-Arachidonoylglycerol on Human Osteoblast Proliferation and DifferentiationGenetic evidence that thyroid hormone is indispensable for prepubertal insulin-like growth factor-I expression and bone acquisition in mice.A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?Telomerase activity promotes osteoblast differentiation by modulating IGF-signaling pathwayDysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem CellsIdentifying growth hormone-regulated enhancers in the Igf1 locus.Promotion of human mesenchymal stem cell osteogenesis by PI3-kinase/Akt signaling, and the influence of caveolin-1/cholesterol homeostasis.Congenic mice provide in vivo evidence for a genetic locus that modulates intrinsic transforming growth factor β1-mediated signaling and bone acquisition.Transcriptome correlation analysis identifies two unique craniosynostosis subtypes associated with IRS1 activation.Zoledrinic Acid Induces Steoblastic Differentiation of Mesenchymal Stem Cells without Change in Hypomethylation Status of OSTERIX PromoterAchieving specificity in Akt signaling in cancer.Mesenchymal stem cells expressing insulin-like growth factor-I (MSCIGF) promote fracture healing and restore new bone formation in Irs1 knockout mice: analyses of MSCIGF autocrine and paracrine regenerative effects.BMP-2 differentially modulates FGF-2 isoform effects in osteoblasts from newborn transgenic miceReversing bone loss by directing mesenchymal stem cells to bone.Immune and inflammatory pathways are involved in inherent bone marrow ossification.IGFBP-2 directly stimulates osteoblast differentiation.Stem cell death and survival in heart regeneration and repair.A Conditional Knockout Mouse Model Reveals a Critical Role of PKD1 in Osteoblast Differentiation and Bone Development.Evaluation of functional dynamics during osseointegration and regeneration associated with oral implants.
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P2860
Akt promotes BMP2-mediated osteoblast differentiation and bone development
description
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
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im März 2009 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2009/03/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/03/01)
@nl
наукова стаття, опублікована в березні 2009
@uk
مقالة علمية (نشرت في مارس 2009)
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name
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@ast
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@en
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@nl
type
label
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@ast
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@en
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@nl
prefLabel
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@ast
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@en
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@nl
P2860
P921
P356
P1476
Akt promotes BMP2-mediated osteoblast differentiation and bone development
@en
P2093
Aditi Mukherjee
Peter Rotwein
P2860
P304
P356
10.1242/JCS.042770
P407
P577
2009-03-01T00:00:00Z