Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration
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Subcellular distribution of Wnt pathway proteins in normal and neoplastic colonAttenuated APC alleles produce functional protein from internal translation initiation.Computational models reveal a passive mechanism for cell migration in the cryptIncreased variability in Apc(Min)/+ intestinal tissue can be measured with microultrasound.COX-2 and cancer: a new approach to an old problemEfficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1.The tumor suppressor Apc controls planar cell polarities central to gut homeostasis.Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systemsNovel association of APC with intermediate filaments identified using a new versatile APC antibodyA simple algebraic cancer equation: calculating how cancers may arise with normal mutation rates.Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.The adenomatous polyposis coli protein.Excess beta-catenin promotes accumulation of transcriptionally active p53.Altered dynamics of intestinal cell maturation in Apc1638N/+ mice.Apc(MIN) modulation of vitamin D secosteroid growth controlAPC/β-catenin-rich complexes at membrane protrusions regulate mammary tumor cell migration and mesenchymal morphologyGenetic enhancement of the Lis1+/- phenotype by a heterozygous mutation in the adenomatous polyposis coli gene.Rectal epithelial apoptosis in familial adenomatous polyposis patients treated with sulindac.Clonal structure of carcinogen-induced intestinal tumors in miceLowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancerCyclooxygenase 2 is up-regulated and localized to macrophages in the intestine of Min mice.Widespread hyperplasia induced by transgenic TGFalpha in ApcMin mice is associated with only regional effects on tumorigenesis.Analysis of masked mutations in familial adenomatous polyposisNonsteroidal anti-inflammatory drug sulindac sulfide suppresses structural protein Nesprin-2 expression in colorectal cancer cellsEllagitannin-rich cloudberry inhibits hepatocyte growth factor induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice.Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi.APC and its modifiers in colon cancer.Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesisCOX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs.NSAIDs inhibit tumorigenesis, but how?Evasion of cell senescence in SHH medulloblastoma.Multiple Roles of APC and its Therapeutic Implications in Colorectal Cancer.Functions of the APC tumor suppressor protein dependent and independent of canonical WNT signaling: implications for therapeutic targeting.
P2860
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P2860
Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration
description
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1997
@ast
im November 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/11/15)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/11/15)
@nl
наукова стаття, опублікована в листопаді 1997
@uk
مقالة علمية (نشرت في 15-11-1997)
@ar
name
Apc gene mutation is associate ...... upon intestinal cell migration
@ast
Apc gene mutation is associate ...... upon intestinal cell migration
@en
Apc gene mutation is associate ...... upon intestinal cell migration
@nl
type
label
Apc gene mutation is associate ...... upon intestinal cell migration
@ast
Apc gene mutation is associate ...... upon intestinal cell migration
@en
Apc gene mutation is associate ...... upon intestinal cell migration
@nl
prefLabel
Apc gene mutation is associate ...... upon intestinal cell migration
@ast
Apc gene mutation is associate ...... upon intestinal cell migration
@en
Apc gene mutation is associate ...... upon intestinal cell migration
@nl
P2093
P3181
P1433
P1476
Apc gene mutation is associate ...... upon intestinal cell migration
@en
P2093
A. Chadburn
C. Martucci
M. M. Bertagnolli
N. N. Mahmoud
R. T. Bilinski
S. K. Boolbol
P304
P3181
P407
P577
1997-11-15T00:00:00Z