AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
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Control of PKA stability and signalling by the RING ligase praja2Structural Insights into the Activation of the RhoA GTPase by the Lymphoid Blast Crisis (Lbc) OncoproteinThe crystal structure of the RhoA-AKAP-Lbc DH-PH domain complexA-kinase-anchoring protein-Lbc anchors IκB kinase β to support interleukin-6-mediated cardiomyocyte hypertrophySignalling scaffolds and local organization of cellular behaviourA-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophyLack of inflammatory gene expression in bats: a unique role for a transcription repressor.The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.Pseudoscaffolds and anchoring proteins: the difference is in the details.Protein kinase A catalytic subunit isoform PRKACA; History, function and physiologyThe MLL recombinome of acute leukemias in 2013.Cyclic nucleotide phosphodiesterases: important signaling modulators and therapeutic targets.RNAi screening in primary human hepatocytes of genes implicated in genome-wide association studies for roles in type 2 diabetes identifies roles for CAMK1D and CDKAL1, among others, in hepatic glucose regulation.Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complexUCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy.AKAPs: the architectural underpinnings of local cAMP signaling.A-kinase anchoring proteins: scaffolding proteins in the heart.Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues.AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency.Curcumin Protects Neurons from Glutamate-Induced Excitotoxicity by Membrane Anchored AKAP79-PKA Interaction NetworkProtein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220A-kinase anchoring proteins as potential drug targets.Quantitative phosphoproteomic analysis reveals a role for serine and threonine kinases in the cytoskeletal reorganization in early T cell receptor activation in human primary T cells.Impaired MEK signaling and SERCA expression promote ER stress and apoptosis in insulin-resistant macrophages and are reversed by exenatide treatment.Multiplexing PKA and ERK1&2 kinases FRET biosensors in living cells using single excitation wavelength dual colour FLIM.The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Ser(16).Src homology 2 domain-containing phosphatase 2 (Shp2) is a component of the A-kinase-anchoring protein (AKAP)-Lbc complex and is inhibited by protein kinase A (PKA) under pathological hypertrophic conditions in the heartThe Orphan G Protein-coupled Receptor GPR17 Negatively Regulates Oligodendrocyte Differentiation via Gαi/o and Its Downstream Effector Molecules.Creating order from chaos: cellular regulation by kinase anchoring.MEK-1 activates C-Raf through a Ras-independent mechanism.Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALINGPhosphodiesterase Isoform Regulation of Cell Proliferation and Fluid Secretion in Autosomal Dominant Polycystic Kidney Disease.PDE8A runs interference to limit PKA inhibition of Raf-1Reciprocal regulation of PKA and Rac signaling.AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption.Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.Local cAMP signaling in disease at a glanceEnhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma.AKAP signaling complexes: pointing towards the next generation of therapeutic targets?cAMP-dependent protein kinase and c-Jun N-terminal kinase mediate stathmin phosphorylation for the maintenance of interphase microtubules during osmotic stress.
P2860
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P2860
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
description
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Dezember 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/12/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/12/01)
@nl
наукова стаття, опублікована в грудні 2010
@uk
مقالة علمية (نشرت في ديسمبر 2010)
@ar
name
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@ast
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@en
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@nl
type
label
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@ast
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@en
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@nl
prefLabel
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@ast
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@en
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@nl
P2093
P2860
P3181
P356
P1433
P1476
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
@en
P2093
Cristina Cellurale
Deborah K. Morrison
F. Donelson Smith
John D. Scott
Lorene K. Langeberg
Roger J. Davis
P2860
P2888
P304
P3181
P356
10.1038/NCB2130
P577
2010-12-01T00:00:00Z
P5875
P6179
1022492534