A common molecular basis for membrane docking and functional priming of synaptic vesicles
about
mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle dockingSynaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic VesiclesThe presynaptic active zoneRIM determines Ca²+ channel density and vesicle docking at the presynaptic active zoneRIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13Molecular Machines Regulating the Release Probability of Synaptic Vesicles at the Active ZoneDistinct initial SNARE configurations underlying the diversity of exocytosisThe Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering FactorsIdentification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosisPresynaptic Calmodulin targets: lessons from structural proteomics.Relating structure and function of inner hair cell ribbon synapses.Cryo-electron tomography reveals a critical role of RIM1α in synaptic vesicle tetheringA stochastic model of active zone material mediated synaptic vesicle docking and priming at resting active zones.Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography.Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/liprin and UNC-10/RIM-dependent interactionsDifferential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1.Mover is a homomeric phospho-protein present on synaptic vesiclesTomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memoryResolving presynaptic structure by electron tomographyAdvances in imaging ultrastructure yield new insights into presynaptic biologyVariable priming of a docked synaptic vesicle.Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter releaseSyntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle primingAlignment of synaptic vesicle macromolecules with the macromolecules in active zone material that direct vesicle docking.UNC-13L, UNC-13S, and Tomosyn form a protein code for fast and slow neurotransmitter release in Caenorhabditis elegans.Ultrafast endocytosis at Caenorhabditis elegans neuromuscular junctions.Ultrafast endocytosis at mouse hippocampal synapses.RIM proteins and their role in synapse function.Protein scaffolds in the coupling of synaptic exocytosis and endocytosis.New insights into molecular players involved in neurotransmitter release.CAPS and Munc13: CATCHRs that SNARE VesiclesPushing synaptic vesicles over the RIM.Mast cell degranulation is negatively regulated by the Munc13-4-binding small-guanosine triphosphatase Rab37.Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse.Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle DockingLoss of MUNC13-1 function causes microcephaly, cortical hyperexcitability, and fatal myasthenia.A Stimulation Function of Synaptotagmin-1 in Ternary SNARE Complex Formation Dependent on Munc18 and Munc13.Three-dimensional imaging of Drosophila motor synapses reveals ultrastructural organizational patterns.3D Analysis of Synaptic Ultrastructure in Organotypic Hippocampal Slice Culture by High-Pressure Freezing and Electron Tomography.
P2860
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P2860
A common molecular basis for membrane docking and functional priming of synaptic vesicles
description
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Juli 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/07/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/07/01)
@nl
наукова стаття, опублікована в липні 2009
@uk
مقالة علمية (نشرت في يوليو 2009)
@ar
name
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@ast
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@en
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@nl
type
label
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@ast
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@en
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@nl
prefLabel
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@ast
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@en
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@nl
P2093
P50
P3181
P1476
A common molecular basis for membrane docking and functional priming of synaptic vesicles
@en
P2093
Léa Siksou
Olivier Pascual
Serge Marty
P3181
P356
10.1111/J.1460-9568.2009.06811.X
P407
P577
2009-07-01T00:00:00Z