Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression
about
The RNA-binding E3 ubiquitin ligase MEX-3C links ubiquitination with MHC-I mRNA degradationDephosphorylation of Carma1 by PP2A negatively regulates T-cell activationPost-transcriptional Regulation of Immunological Responses through RiboclusteringRNA recognition by Roquin in posttranscriptional gene regulationRoquin--a multifunctional regulator of immune homeostasisMicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and developmentThe ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNAStructural basis for RNA recognition in roquin-mediated post-transcriptional gene regulationRoquin binding to target mRNAs involves a winged helix-turn-helix motifRoquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40ICOS Co-Stimulation: Friend or Foe?Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases?Loss of Roquin induces early death and immune deregulation but not autoimmunityRoquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasisA negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiationUsing Murine Models to Investigate Tumor-Lymphoid Interactions: Spotlight on Chronic Lymphocytic Leukemia and Angioimmunoblastic T-Cell Lymphoma.AU-rich element-mediated mRNA decay can occur independently of the miRNA machinery in mouse embryonic fibroblasts and Drosophila S2-cellsT-cell subsets in the germinal center.Molecular control of Tfh-cell differentiation by Roquin family proteins.Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.ROQUIN/RC3H1 alterations are not found in angioimmunoblastic T-cell lymphoma.STAT3 signaling induces the differentiation of human ICOS(+) CD4 T cells helping B lymphocytes.Relationship of GW/P-bodies with stress granules.RNA-binding protein hnRNPLL regulates mRNA splicing and stability during B-cell to plasma-cell differentiationA p85α-osteopontin axis couples the receptor ICOS to sustained Bcl-6 expression by follicular helper and regulatory T cells.New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins.Tumor suppressor TSC1 is critical for T-cell anergyAttenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation.T cell Receptor Signal Transduction in T lymphocytes.A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions.MicroRNA-mediated regulation of T helper cell differentiation and plasticity.Integrating post-transcriptional regulation into the embryonic stem cell gene regulatory network.T-follicular helper cell differentiation and the co-option of this pathway by non-helper cells.The darker side of follicular helper T cells: from autoimmunity to immunodeficiency.Post-transcriptional regulatory networks in immunity.Control of TFH cell numbers: why and how?DDX6 and its orthologs as modulators of cellular and viral RNA expression.Post-transcriptional coordination of immunological responses by RNA-binding proteins.Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing
P2860
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P2860
Roquin binds inducible costimulator mRNA and effectors of mRNA decay to induce microRNA-independent post-transcriptional repression
description
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im August 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/08/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/08/01)
@nl
наукова стаття, опублікована в серпні 2010
@uk
مقالة علمية (نشرت في أغسطس 2010)
@ar
name
Roquin binds inducible costimu ...... ost-transcriptional repression
@ast
Roquin binds inducible costimu ...... ost-transcriptional repression
@en
Roquin binds inducible costimu ...... ost-transcriptional repression
@nl
type
label
Roquin binds inducible costimu ...... ost-transcriptional repression
@ast
Roquin binds inducible costimu ...... ost-transcriptional repression
@en
Roquin binds inducible costimu ...... ost-transcriptional repression
@nl
prefLabel
Roquin binds inducible costimu ...... ost-transcriptional repression
@ast
Roquin binds inducible costimu ...... ost-transcriptional repression
@en
Roquin binds inducible costimu ...... ost-transcriptional repression
@nl
P2093
P50
P921
P3181
P356
P1433
P1476
Roquin binds inducible costimu ...... ost-transcriptional repression
@en
P2093
Christine Wolf
Kai P. Hoefig
Katharina U. Vogel
Vigo Heissmeyer
Xiaozhong Wang
P304
P3181
P356
10.1038/NI.1902
P407
P577
2010-08-01T00:00:00Z