Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
about
Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2ERp29 induces breast cancer cell growth arrest and survival through modulation of activation of p38 and upregulation of ER stress protein p58IPKNck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stressA crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cellsAssociation with endoplasmic reticulum promotes proteasomal degradation of GADD34 proteinSKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxiaNck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translationA conserved domain of herpes simplex virus ICP34.5 regulates protein phosphatase complex in mammalian cellsGene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control.ERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosisRegulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cellsCellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegenerationHuman BAG-1 proteins bind to the cellular stress response protein GADD34 and interfere with GADD34 functionsGADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptorApoptosis, autophagy and unfolded protein response pathways in Arbovirus replication and pathogenesisMelanoma and the Unfolded Protein ResponseEndoplasmic reticulum stress: a novel mechanism and therapeutic target for cardiovascular diseasesCell-Free Protein Synthesis: Pros and Cons of Prokaryotic and Eukaryotic SystemsThe unfolded protein response in multiple sclerosisAnticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stressSpliced leader RNA silencing (SLS) - a programmed cell death pathway in Trypanosoma brucei that is induced upon ER stressTranslational control by heme-regulated eIF2α kinase during erythropoiesisNutrient sensing, metabolism, and cell growth controlER stress-induced cell death mechanismsIntegration of the unfolded protein and oxidative stress responses through SKN-1/NrfCoronavirus gene 7 counteracts host defenses and modulates virus virulenceDivergent effects of PERK and IRE1 signaling on cell viabilityWest Nile Virus Infection Activates the Unfolded Protein Response, Leading to CHOP Induction and ApoptosisFrom HLA-B27 to spondyloarthritis: a journey through the ER.Protein phosphatase type 1 regulates ion homeostasis in Saccharomyces cerevisiae.ER Stress-Mediated Signaling: Action Potential and Ca(2+) as Key PlayersReview: Modulating the unfolded protein response to prevent neurodegeneration and enhance memoryAdvances and New Concepts in Alcohol-Induced Organelle Stress, Unfolded Protein Responses and Organ DamageEndoplasmic reticulum quality control and systemic amyloid disease: Impacting protein stability from the inside outGadd34 functional domains involved in growth suppression and apoptosisNeurabins recruit protein phosphatase-1 and inhibitor-2 to the actin cytoskeletonThe human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activitySalicylates trigger protein synthesis inhibition in a protein kinase R-like endoplasmic reticulum kinase-dependent manner
P2860
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P2860
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
name
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@ast
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@en
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@nl
type
label
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@ast
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@en
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@nl
prefLabel
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@ast
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@en
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@nl
P2860
P50
P921
P3181
P356
P1476
Feedback inhibition of the unf ...... dephosphorylation of eIF2alpha
@en
P2093
P2860
P304
P3181
P356
10.1083/JCB.153.5.1011
P407
P577
2001-05-01T00:00:00Z