Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor
about
Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancerAndrogen receptor and prostate cancer stem cells: biological mechanisms and clinical implicationsGenetically engineered mouse models of prostate cancerTestosterone therapy in men with testosterone deficiency: Are we beyond the point of no return?The importance of non-nuclear AR signaling in prostate cancer progression and therapeutic resistanceId4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTENA computational systems approach identifies synergistic specification genes that facilitate lineage conversion to prostate tissueLoss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signalingAndrogen receptor (AR) physiological roles in male and female reproductive systems: lessons learned from AR-knockout mice lacking AR in selective cellsIncreased CK5/CK8-positive intermediate cells with stromal smooth muscle cell atrophy in the mice lacking prostate epithelial androgen receptorProstate progenitor cells proliferate in response to castration.Repression of androgen receptor transcription through the E2F1/DNMT1 axis.Finasteride treatment alters tissue specific androgen receptor expression in prostate tissues.Molecular genetics of prostate cancer: new prospects for old challengesAltered differentiation and proliferation of prostate epithelium in mice lacking the androgen receptor cofactor p44/WDR77Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.Androgen receptor drives cellular senescence.The impact of point mutations in the human androgen receptor: classification of mutations on the basis of transcriptional activityPioglitazone attenuates prostatic enlargement in diet-induced insulin-resistant rats by altering lipid distribution and hyperinsulinaemia.Deletion of androgen receptor in the smooth muscle of the seminal vesicles impairs secretory function and alters its responsiveness to exogenous testosterone and estradiolAltered prostate epithelial development and IGF-1 signal in mice lacking the androgen receptor in stromal smooth muscle cells.Length of the human androgen receptor glutamine tract determines androgen sensitivity in vivo.Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism.Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.Androgens and estrogens in benign prostatic hyperplasia: past, present and future.Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts.Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptorAndrogen Receptor-Mediated Growth Suppression of HPr-1AR and PC3-Lenti-AR Prostate Epithelial Cells.Increased infiltrated macrophages in benign prostatic hyperplasia (BPH): role of stromal androgen receptor in macrophage-induced prostate stromal cell proliferationAndrogen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells.Targeting androgen receptor to suppress macrophage-induced EMT and benign prostatic hyperplasia (BPH) development.Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokinesAndrogen hormone action in prostatic carcinogenesis: stromal androgen receptors mediate prostate cancer progression, malignant transformation and metastasis.Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis.Antiandrogen Therapy with Hydroxyflutamide or Androgen Receptor Degradation Enhancer ASC-J9 Enhances BCG Efficacy to Better Suppress Bladder Cancer Progression.New therapeutic approach to suppress castration-resistant prostate cancer using ASC-J9 via targeting androgen receptor in selective prostate cells.Region-specific growth effects in the developing rat prostate following fetal exposure to estrogenic ultraviolet filters.Loss of epithelial oestrogen receptor α inhibits oestrogen-stimulated prostate proliferation and squamous metaplasia via in vivo tissue selective knockout modelsAndrogen receptor is a tumor suppressor and proliferator in prostate cancer.Targeting the stromal androgen receptor in primary prostate tumors at earlier stages.
P2860
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P2860
Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor
description
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2007
@ast
im Juli 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/07/31)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/07/31)
@nl
наукова стаття, опублікована в липні 2007
@uk
name
Increased prostate cell prolif ...... e epithelial androgen receptor
@ast
Increased prostate cell prolif ...... e epithelial androgen receptor
@en
Increased prostate cell prolif ...... e epithelial androgen receptor
@nl
type
label
Increased prostate cell prolif ...... e epithelial androgen receptor
@ast
Increased prostate cell prolif ...... e epithelial androgen receptor
@en
Increased prostate cell prolif ...... e epithelial androgen receptor
@nl
prefLabel
Increased prostate cell prolif ...... e epithelial androgen receptor
@ast
Increased prostate cell prolif ...... e epithelial androgen receptor
@en
Increased prostate cell prolif ...... e epithelial androgen receptor
@nl
P2093
P2860
P3181
P356
P1476
Increased prostate cell prolif ...... e epithelial androgen receptor
@en
P2093
Caixia Zhang
Chawnshang Chang
Chun-Te Wu
Meng-Ying Tsai
Saleh Altuwaijri
Shu-Pin Huang
Shuyuan Yeh
William A. Ricke
Yuanjie Niu
P2860
P304
12679–12684
P3181
P356
10.1073/PNAS.0704940104
P407
P577
2007-07-31T00:00:00Z