DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping
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DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down SyndromeInterdependence of nutrient metabolism and the circadian clock system: Importance for metabolic healthEmerging models for the molecular basis of mammalian circadian timingMetabolism as an integral cog in the mammalian circadian clockworkDesign and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitorsPhosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period lengthRegulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2.GSK-3: Functional Insights from Cell Biology and Animal Models.Tumor suppressor DYRK1A effects on proliferation and chemoresistance of AML cells by downregulating c-Myc.Molecular basis for blue light-dependent phosphorylation of Arabidopsis cryptochrome 2.Identification of small molecule activators of cryptochromeMolecular components of the Mammalian circadian clock.Phosphorylation and inactivation of glycogen synthase kinase 3β (GSK3β) by dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A)Mammalian sirtuins and energy metabolismSirtuin 1 in lipid metabolism and obesity.Circadian rhythms and mood regulation: insights from pre-clinical modelsAltered regulation of tau phosphorylation in a mouse model of down syndrome agingDisruptive de novo mutations of DYRK1A lead to a syndromic form of autism and IDUSP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian ClockCircadian rhythmicity of active GSK3 isoforms modulates molecular clock gene rhythms in the suprachiasmatic nucleus.USP2a protein deubiquitinates and stabilizes the circadian protein CRY1 in response to inflammatory signalsThe NAD(+)-dependent protein deacetylase activity of SIRT1 is regulated by its oligomeric statusGlycogen synthase kinase is a regulator of the circadian clock of Neurospora crassa.Disruption of circadian rhythmicity and suprachiasmatic action potential frequency in a mouse model with constitutive activation of glycogen synthase kinase 3.SIRT1 and energy metabolism.Genetics of circadian rhythms in Mammalian model organisms.Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complexLithium effects on circadian rhythms in fibroblasts and suprachiasmatic nucleus slices from Cry knockout mice.Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock.Activation, regulation, and inhibition of DYRK1A.MNB/DYRK1A as a multiple regulator of neuronal development.Kinases and phosphatases in the mammalian circadian clock.Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control.Circadian rhythms in liver physiology and liver diseases.Solving the mystery of human sleep schedules one mutation at a time.A central role for ubiquitination within a circadian clock protein modification codeHow is the inner circadian clock controlled by interactive clock proteins?: Structural analysis of clock proteins elucidates their physiological role.USP2 regulates the intracellular localization of PER1 and circadian gene expression.Molecular modulators of the circadian clock: lessons from flies and mice.Biological hypotheses and biomarkers of bipolar disorder.
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P2860
DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping
description
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
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im April 2010 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2010/04/01)
@sk
vědecký článek publikovaný v roce 2010
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wetenschappelijk artikel (gepubliceerd op 2010/04/01)
@nl
наукова стаття, опублікована у квітні 2010
@uk
مقالة علمية (نشرت في أبريل 2010)
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name
DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
@ast
DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
@en
DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
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type
label
DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
@ast
DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
@en
DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
@nl
prefLabel
DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
@ast
DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
@en
DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
@nl
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DYRK1A and glycogen synthase k ...... CRY2 for circadian timekeeping
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P2093
Mihoko Sakai
Yoshitaka Fukada
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P304
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10.1128/MCB.01047-09
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P577
2010-02-01T00:00:00Z