Testis determination requires insulin receptor family function in mice
about
Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determinationGadd45g is essential for primary sex determination, male fertility and testis developmentInsulin receptor-related receptor as an extracellular alkali sensorBuilding the mammalian testis: origins, differentiation, and assembly of the component cell populationsHuman conditions of insulin-like growth factor-I (IGF-I) deficiencyInsulin receptor signaling in normal and insulin-resistant statesThe High Mobility Group Box Transcription Factor Nhp6Ap enters the nucleus by a calmodulin-dependent, Ran-independent pathway.Genetic control of testis developmentInsulin receptor substrate 2 is required for testicular developmentInsulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in miceCoordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTPInsulin and insulin like growth factor II endocytosis and signaling via insulin receptor BA crayfish insulin-like-binding protein: another piece in the androgenic gland insulin-like hormone puzzle is revealedA comparative structural bioinformatics analysis of the insulin receptor family ectodomain based on phylogenetic information.Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.Switching on sex: transcriptional regulation of the testis-determining gene SryA sexual shift induced by silencing of a single insulin-like gene in crayfish: ovarian upregulation and testicular degeneration.Unique expression pattern of the three insulin receptor family members in the rat mammary gland: dominance of IGF-1R and IRR over the IR, and cyclical IGF-1R expression.The road to maleness: from testis to Wolffian duct.Insulin: its role in the central control of reproductionMechanisms of activation of receptor tyrosine kinases: monomers or dimers.Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.Disorders of sex development: new genes, new concepts.Regulation of male sex determination: genital ridge formation and Sry activation in mice.Identification of a testis-enriched heat shock protein and fourteen members of Hsp70 family in the swamp eel.Primary cilia and coordination of receptor tyrosine kinase (RTK) signalling.Global proteomics analysis of testis and ovary in adult zebrafish (Danio rerio).The emerging role of insulin-like growth factors in testis development and function.Mitochondrial maintenance failure in aging and role of sexual dimorphism.One tissue, two fates: molecular genetic events that underlie testis versus ovary development.Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function.New members of the insulin family: regulators of metabolism, growth and now ... reproduction.From SRY to SOX9: mammalian testis differentiation.Expression and localization of growth factors and their receptors in the mammalian testis. Part I: Fibroblast growth factors and insulin-like growth factors.Transcriptomic responses to environmental temperature by turtles with temperature-dependent and genotypic sex determination assessed by RNAseq inform the genetic architecture of embryonic gonadal development.Mechanisms of Disease: normal and abnormal gonadal development and sex determination in mammals.The makings of maleness: towards an integrated view of male sexual development.Follistatin-like 3 (FSTL3) mediated silencing of transforming growth factor β (TGFβ) signaling is essential for testicular aging and regulating testis sizeHermaphrodism and sex reversal associated with the dominant hemimelia mutation in XY mice.The molecular and cellular basis of gonadal sex reversal in mice and humans.
P2860
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P2860
Testis determination requires insulin receptor family function in mice
description
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2003
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scientific journal article
@en
vedecký článok (publikovaný 2003/11/20)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/11/20)
@nl
наукова стаття, опублікована в листопаді 2003
@uk
مقالة علمية (نشرت في 20-11-2003)
@ar
name
Testis determination requires insulin receptor family function in mice
@ast
Testis determination requires insulin receptor family function in mice
@en
Testis determination requires insulin receptor family function in mice
@nl
type
label
Testis determination requires insulin receptor family function in mice
@ast
Testis determination requires insulin receptor family function in mice
@en
Testis determination requires insulin receptor family function in mice
@nl
prefLabel
Testis determination requires insulin receptor family function in mice
@ast
Testis determination requires insulin receptor family function in mice
@en
Testis determination requires insulin receptor family function in mice
@nl
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P921
P356
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P1476
Testis determination requires insulin receptor family function in mice
@en
P2093
Jean-Dominique Vassalli
Jussi Merenmies
Luis F. Parada
Sunita Verma-Kurvari
P2888
P304
P356
10.1038/NATURE02059
P407
P577
2003-11-20T00:00:00Z
P5875
P6179
1042054221