Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout
about
Alterations in T-tubule and dyad structure in heart disease: challenges and opportunities for computational analysesA network-oriented perspective on cardiac calcium signalingElevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasisIntegrating multi-scale data to create a virtual physiological mouse heart.Regulation of Cardiomyocyte T-Tubular Structure: Opportunities for Therapy.AutoTT: automated detection and analysis of T-tubule architecture in cardiomyocytesInhibition of miR-25 improves cardiac contractility in the failing heart.Cardiac T-Tubule Microanatomy and Function.Prominent heart organ-level performance deficits in a genetic model of targeted severe and progressive SERCA2 deficiency.T-tubule disruption promotes calcium alternans in failing ventricular myocytes: mechanistic insights from computational modelingGene co-expression network analysis provides novel insights into myostatin regulation at three different mouse developmental timepoints.In situ single photon confocal imaging of cardiomyocyte T-tubule system from Langendorff-perfused heartsTargeting cardiomyocyte Ca2+ homeostasis in heart failure.Ryanodine receptor cluster fragmentation and redistribution in persistent atrial fibrillation enhance calcium release.Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity.Ca(2+)-Clock-Dependent Pacemaking in the Sinus Node Is Impaired in Mice with a Cardiac Specific Reduction in SERCA2 AbundanceEmerging mechanisms of T-tubule remodelling in heart failure.Critical roles of junctophilin-2 in T-tubule and excitation-contraction coupling maturation during postnatal developmentThe Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation.No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium.Reversibility of T-tubule remodelling in heart failure: mechanical load as a dynamic regulator of the T-tubules.Calcium signalling in developing cardiomyocytes: implications for model systems and disease.Species-Dependent Mechanisms of Cardiac Arrhythmia: A Cellular Focus.Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice.Mitochondrial pathways to cardiac recovery: TFAM.Long-term levosimendan treatment improves systolic function and myocardial relaxation in mice with cardiomyocyte-specific disruption of the Serca2 gene.miR-25 Tough Decoy Enhances Cardiac Function in Heart Failure.A model of cardiac ryanodine receptor gating predicts experimental Ca2+-dynamics and Ca2+-triggered arrhythmia in the long QT syndrome.Variable t-tubule organization and Ca2+ homeostasis across the atria.
P2860
Q27021273-1D802479-CC11-4E47-8A92-2903BD1A6D5DQ27023389-B6764F3A-98CD-4273-895F-60C67A6E8F7EQ27302066-49124305-D6F6-4B2A-9332-8DEBA0A276CFQ30734214-4762D995-8A7B-427C-9CE2-31518FA10C22Q33653885-99A22FA7-C82F-4A0E-AF44-8C8984590745Q33804017-793152C1-4B5E-4A6D-A80C-BF9306C6D8D9Q34040266-7FF64280-329F-4DF5-A8F3-6E59FE75F8DAQ34545692-B5DA77FA-36ED-4E1B-81B8-FBA1EB92BCCFQ35041411-6438E141-696B-4846-9F81-2025A6A79A21Q35069142-6CE9839D-1462-448A-8EE0-23CD15671E9CQ35563984-CD1A9CB4-426D-40F1-99C4-8353A106D2FBQ35575378-B9D88674-1265-44B4-ADE4-222B9A42BABEQ35763705-9013EC95-A9B5-476F-B877-89506293E5DCQ36287960-7E2770ED-BE47-4526-B6BA-D029768A76EBQ36770437-4DA044BF-6B07-4D55-88FD-A802DF388E80Q36958008-CC20FED1-1F82-4E2D-AB83-8976535D76ECQ36968869-7549C1D8-0E67-4F84-ABC5-05C78BDA0549Q37187489-77A4E653-11B0-4F45-87B0-8E39F7750448Q37198437-AC0B4F29-340D-4C90-9B0C-F0CB068EBD46Q38048564-99089615-BC94-40A5-B4B3-2E36043802DFQ38076375-53997EC9-B1CD-4090-9933-8DF38ACCAFE8Q38340336-D5294EE7-2BA1-494E-A688-C79E59F0C349Q39281856-E853358F-6DC9-46DD-B29A-2A253FE264C8Q41841957-48479820-C1DF-4599-BBAA-6BAED775AE7CQ41980044-6506D70A-0F73-4FED-A176-DEF5B74EAC5FQ46728107-ED1DACC7-AE3F-4DFF-B3C8-B2BDEE01B30EQ47256616-96BEF95B-4D60-4A27-B589-7F5988CA0D46Q47666081-4F217735-20F8-41A6-B1DD-1E77615CE9EBQ51075465-313573E7-5AE8-490C-A937-1A914032EA3A
P2860
Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout
description
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2012
@ast
im März 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/03/06)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/03/06)
@nl
наукова стаття, опублікована в березні 2012
@uk
name
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@ast
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@en
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@nl
type
label
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@ast
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@en
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@nl
prefLabel
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@ast
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@en
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Extreme sarcoplasmic reticulum ...... modeling after Serca2 knockout
@en
P2093
Fredrik Swift
Kristin Brevik Andersson
Leiv Øyehaug
Ulla Helene Enger
William E. Louch
P2860
P304
P3181
P356
10.1073/PNAS.1120172109
P407
P577
2012-03-06T00:00:00Z