Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation
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The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in miceEpigenetic regulation in chondrocyte phenotype maintenance for cell-based cartilage repairA hypomorphic allele reveals an important role of inturned in mouse skeletal developmentDisruption of insulin-like growth factor-I expression in type IIalphaI collagen-expressing cells reduces bone length and width in mice.In vivo genetic evidence for suppressing vascular and soft-tissue calcification through the reduction of serum phosphate levels, even in the presence of high serum calcium and 1,25-dihydroxyvitamin d levelsPartial rescue of postnatal growth plate abnormalities in Ihh mutants by expression of a constitutively active PTH/PTHrP receptorHedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract.Dietary and genetic evidence for phosphate toxicity accelerating mammalian aging.Zfp521 is a target gene and key effector of parathyroid hormone-related peptide signaling in growth plate chondrocytes.Cartilage-specific overexpression of ERRγ results in Chondrodysplasia and reduced chondrocyte proliferation.Deletion of Zfp521 rescues the growth plate phenotype in a mouse model of Jansen metaphyseal chondrodysplasiaChondrocytic Atf4 regulates osteoblast differentiation and function via Ihh.The regulation of embryo implantation and endometrial decidualization by progesterone receptor signaling.Deletion of IFT80 Impairs Epiphyseal and Articular Cartilage Formation Due to Disruption of Chondrocyte Differentiation.Vegfa regulates perichondrial vascularity and osteoblast differentiation in bone developmentIndian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular boneRegulation of murine normal and stress-induced erythropoiesis by Desert Hedgehog.Signaling networks that control the lineage commitment and differentiation of bone cells.Signaling and transcriptional regulation in osteoblast commitment and differentiationA review of hedgehog signaling in cranial bone developmentCol2-Cre recombinase is co-expressed with endogenous type II collagen in embryonic renal epithelium and drives development of polycystic kidney disease following inactivation of ciliary genes.In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasisGeneration of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase.Hedgehog Signalling in the Embryonic Mouse ThymusInactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse model.Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice.Smoothened antagonists: a promising new class of antitumor agents.Indian Hedgehog, a critical modulator in osteoarthritis, could be a potential therapeutic target for attenuating cartilage degeneration disease.The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling.Clock genes influence gene expression in growth plate and endochondral ossification in mice.Col11a1 Regulates Bone Microarchitecture during Embryonic Development.Conditional Deletion of Indian Hedgehog in Limb Mesenchyme Results in Complete Loss of Growth Plate Formation but Allows Mature Osteoblast Differentiation.An Hh-dependent pathway in lateral plate mesoderm enables the generation of left/right asymmetry.Positive regulation by γ-aminobutyric acid B receptor subunit-1 of chondrogenesis through acceleration of nuclear translocation of activating transcription factor-4.Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice.Development of the post-natal growth plate requires intraflagellar transport proteins.Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development.Integration of phosphatidylinositol 3-kinase, Akt kinase, and Smad signaling pathway in BMP-2-induced osterix expression.Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling.
P2860
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P2860
Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2005/12/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/01)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في ديسمبر 2005)
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name
Conditional deletion of Indian ...... al endochondral bone formation
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Conditional deletion of Indian ...... al endochondral bone formation
@en
Conditional deletion of Indian ...... al endochondral bone formation
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type
label
Conditional deletion of Indian ...... al endochondral bone formation
@ast
Conditional deletion of Indian ...... al endochondral bone formation
@en
Conditional deletion of Indian ...... al endochondral bone formation
@nl
prefLabel
Conditional deletion of Indian ...... al endochondral bone formation
@ast
Conditional deletion of Indian ...... al endochondral bone formation
@en
Conditional deletion of Indian ...... al endochondral bone formation
@nl
P2093
P3181
P356
P1476
Conditional deletion of Indian ...... al endochondral bone formation
@en
P2093
Beate Lanske
Desi W. Soegiarto
Fanxin Long
Mohammed S. Razzaque
P304
P3181
P356
10.1002/PATH.1870
P577
2005-12-01T00:00:00Z