Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology
about
HDAC3 is negatively regulated by the nuclear protein DBC1DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbαThe role of circadian clocks in metabolic diseaseDual roles of FBXL3 in the mammalian circadian feedback loops are important for period determination and robustness of the clockBeyond the monoaminergic hypothesis: neuroplasticity and epigenetic changes in a transgenic mouse model of depressionEpigenetic Activation of Wnt/β-Catenin Signaling in NAFLD-Associated HepatocarcinogenesisRegulation of metabolism: the circadian clock dictates the timeTranscriptional repression of mitochondrial function in aging: a novel role for the silencing mediator of retinoid and thyroid hormone receptors co-repressorEvolving roles of circadian rhythms in liver homeostasis and pathologyIncreased sensitivity of the circadian system to temporal changes in the feeding regime of spontaneously hypertensive rats - a potential role for Bmal2 in the liverHistone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fatTherapeutic applications of circadian rhythms for the cardiovascular systemHuman blood metabolite timetable indicates internal body timeCircadian regulation of metabolismFasting and high-fat diet alter histone deacetylase expression in the medial hypothalamusThyroid hormone signaling in vivo requires a balance between coactivators and corepressorsCircadian integration of metabolism and energeticsChronobiology and obesity: Interactions between circadian rhythms and energy regulation.Circadian rhythms and metabolic syndrome: from experimental genetics to human disease.Structure and expression of two nuclear receptor genes in marsupials: insights into the evolution of the antisense overlap between the α-thyroid hormone receptor and Rev-erbα.Plasticity and specificity of the circadian epigenome.Metabolism control by the circadian clock and vice versa.Transcriptional coregulators: fine-tuning metabolism.E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alphaThe interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo.The function of nuclear receptors in regulation of female reproduction and embryogenesis in the red flour beetle, Tribolium castaneum.Association between mammalian lifespan and circadian free-running period: the circadian resonance hypothesis revisited.PPARs in Rhythmic Metabolic Regulation and Implications in Health and Disease.HDAC3 is a critical negative regulator of long-term memory formation.Transcriptome comparison between fetal and adult mouse livers: implications for circadian clock mechanismsNCoR1 is a conserved physiological modulator of muscle mass and oxidative function.An intensity ratio of interlocking loops determines circadian period length.Reciprocal occupancy of BCL6 and STAT5 on Growth Hormone target genes: contrasting transcriptional outcomes and promoter-specific roles of p300 and HDAC3.Rev-erb-alpha: an integrator of circadian rhythms and metabolismMetabolism and the circadian clock converge.Early chronotype and tissue-specific alterations of circadian clock function in spontaneously hypertensive rats.Regulation of SMRT corepressor dimerization and composition by MAP kinase phosphorylation.Nuclear receptor corepressor SMRT regulates mitochondrial oxidative metabolism and mediates aging-related metabolic deteriorationMonoaminergic and neuropeptidergic neurons have distinct expression profiles of histone deacetylases.Differential effect of HDAC3 on cytoplasmic and nuclear huntingtin aggregates.
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P2860
Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology
description
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2008
@ast
scientific journal article
@en
vedecký článok (publikovaný 2008/12/18)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/12/18)
@nl
наукова стаття, опублікована в грудні 2008
@uk
مقالة علمية (نشرت في 18-12-2008)
@ar
name
Nuclear receptor corepressor a ...... circadian metabolic physiology
@ast
Nuclear receptor corepressor a ...... circadian metabolic physiology
@en
Nuclear receptor corepressor a ...... circadian metabolic physiology
@nl
type
label
Nuclear receptor corepressor a ...... circadian metabolic physiology
@ast
Nuclear receptor corepressor a ...... circadian metabolic physiology
@en
Nuclear receptor corepressor a ...... circadian metabolic physiology
@nl
prefLabel
Nuclear receptor corepressor a ...... circadian metabolic physiology
@ast
Nuclear receptor corepressor a ...... circadian metabolic physiology
@en
Nuclear receptor corepressor a ...... circadian metabolic physiology
@nl
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Nuclear receptor corepressor a ...... circadian metabolic physiology
@en
P2093
Adetoun Adeniji-Adele
Jacqueline Avila
Katherine Meyers
Kirstin Leitner
Klaus H. Kaestner
Maja Bućan
Mitchell A. Lazar
Rexford S. Ahima
Shannon E. Mullican
Theresa Alenghat
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P2888
P304
P3181
P356
10.1038/NATURE07541
P407
P577
2008-12-18T00:00:00Z
P5875
P6179
1004302503