Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction
about
Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junctionRapsyn mutations in humans cause endplate acetylcholine-receptor deficiency and myasthenic syndromeDistinct domains of MuSK mediate its abilities to induce and to associate with postsynaptic specializationsGlutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubesStructural basis of agrin-LRP4-MuSK signalingThe role of agrin in synaptic development, plasticity and signaling in the central nervous systemThe neurogenetics of alternative splicingVAChT overexpression increases acetylcholine at the synaptic cleft and accelerates aging of neuromuscular junctionsAberrant development of motor axons and neuromuscular synapses in erbB2-deficient miceAgrin and synaptic laminin are required to maintain adult neuromuscular junctionsRegulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junctionAgrin isoforms with distinct amino termini: differential expression, localization, and functionMapping of the laminin-binding site of the N-terminal agrin domain (NtA).Achieving Acetylcholine Receptor Clustering in Tissue-Engineered Skeletal Muscle Constructs In vitro through a Materials-Directed Agrin Delivery Approach.Induction of myasthenia by immunization against muscle-specific kinase.SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysisC. elegans agrin is expressed in pharynx, IL1 neurons and distal tip cells and does not genetically interact with genes involved in synaptogenesis or muscle function.Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors.Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain.Formation of the neuromuscular junction. Agrin and its unusual receptors.Agrin promotes synaptic differentiation by counteracting an inhibitory effect of neurotransmitterOrganization of synaptic myonuclei by Syne proteins and their role during the formation of the nerve-muscle synapseCollagen XIX is expressed by interneurons and contributes to the formation of hippocampal synapses.Ontogenomic study of the relationship between number of gene splice variants and GO categorization.Laminins and human disease.LRP4 is critical for neuromuscular junction maintenanceThe agrin/muscle-specific kinase pathway: new targets for autoimmune and genetic disorders at the neuromuscular junction.The MuSK activator agrin has a separate role essential for postnatal maintenance of neuromuscular synapses.Early detachment of neuromuscular junction proteins in ALS mice with SODG93A mutation.A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3.The basement membrane/basal lamina of skeletal muscle.Injection of a soluble fragment of neural agrin (NT-1654) considerably improves the muscle pathology caused by the disassembly of the neuromuscular junction.A valid mouse model of AGRIN-associated congenital myasthenic syndrome.The impact of alternative splicing in vivo: mouse models show the way.Systemic, postsymptomatic antisense oligonucleotide rescues motor unit maturation delay in a new mouse model for type II/III spinal muscular atrophy.Role of extracellular matrix proteins and their receptors in the development of the vertebrate neuromuscular junctionNerve-independent formation of a topologically complex postsynaptic apparatus.Seeking long-term relationship: axon and target communicate to organize synaptic differentiation.LG2 agrin mutation causing severe congenital myasthenic syndrome mimics functional characteristics of non-neural (z-) agrin.Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction.
P2860
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P2860
Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction
description
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
@ast
im Mai 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/05/01)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/05/01)
@nl
наукова стаття, опублікована в травні 1999
@uk
научни чланак (објављен 1999/05/01)
@sr
name
Alternatively spliced isoforms ...... at the neuromuscular junction
@ast
Alternatively spliced isoforms ...... at the neuromuscular junction
@en
Alternatively spliced isoforms ...... at the neuromuscular junction
@nl
type
label
Alternatively spliced isoforms ...... at the neuromuscular junction
@ast
Alternatively spliced isoforms ...... at the neuromuscular junction
@en
Alternatively spliced isoforms ...... at the neuromuscular junction
@nl
prefLabel
Alternatively spliced isoforms ...... at the neuromuscular junction
@ast
Alternatively spliced isoforms ...... at the neuromuscular junction
@en
Alternatively spliced isoforms ...... at the neuromuscular junction
@nl
P2093
P3181
P1433
P1476
Alternatively spliced isoforms ...... at the neuromuscular junction
@en
P2093
P3181
P356
10.1016/S0896-6273(00)80751-5
P407
P577
1999-05-01T00:00:00Z