Nucleotide receptor signaling in murine macrophages is linked to reactive oxygen species generation
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Activation of P2X(7) receptor by ATP plays an important role in regulating inflammatory responses during acute viral infectionP2X7 receptor activation induces reactive oxygen species formation and cell death in murine EOC13 microgliaNeuronal P2X7 receptor-induced reactive oxygen species production contributes to nociceptive behavior in miceMutation of putative N-linked glycosylation sites on the human nucleotide receptor P2X7 reveals a key residue important for receptor function.The role of the P2X₇ receptor in infectious diseases.NLRP3 inflammasome activation and interleukin-1β release in macrophages require calcium but are independent of calcium-activated NADPH oxidasesActivation of the transcription factor FosB/activating protein-1 (AP-1) is a prominent downstream signal of the extracellular nucleotide receptor P2RX7 in monocytic and osteoblastic cells.Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic actionGlibenclamide decreases ATP-induced intracellular calcium transient elevation via inhibiting reactive oxygen species and mitochondrial activity in macrophages.Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions.Rhein antagonizes P2X7 receptor in rat peritoneal macrophagesPivotal role of reactive oxygen species in differential regulation of lipopolysaccharide-induced prostaglandins production in macrophagesExtracellular ATP and other nucleotides-ubiquitous triggers of intercellular messenger release.The nucleotide receptor P2RX7 mediates ATP-induced CREB activation in human and murine monocytic cells.Pharmacological evidence for the stimulation of NADPH oxidase by P2X(7) receptors in mouse submandibular glands.Nucleotide receptor P2RX7 stimulation enhances LPS-induced interferon-β production in murine macrophagesCell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor traffickingUse of anti-cancer drugs, mitocans, to enhance the immune responses against tumors.The P2X(7) receptor and intracellular pathogens: a continuing struggle.Infection with Leishmania major induces a cellular stress response in macrophagesPurinergic signalling and immune cells.P2X7 receptor-pannexin 1 interaction mediates extracellular alpha-synuclein-induced ATP release in neuroblastoma SH-SY5Y cells.Extracellular ATP may contribute to tissue repair by rapidly stimulating purinergic receptor X7-dependent vascular endothelial growth factor release from primary human monocytes.A combined omics study on activated macrophages--enhanced role of STATs in apoptosis, immunity and lipid metabolism.Emodin inhibits ATP-induced IL-1β secretion, ROS production and phagocytosis attenuation in rat peritoneal macrophages via antagonizing P2X₇ receptor.Functional coupling expression of COX-2 and cPLA2 induced by ATP in rat vascular smooth muscle cells: role of ERK1/2, p38 MAPK, and NF-kappaB.Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage.Regulation of innate immunity by the nucleotide pathway in children with idiopathic nephrotic syndrome.
P2860
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P2860
Nucleotide receptor signaling in murine macrophages is linked to reactive oxygen species generation
description
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
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im Mai 2007 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2007/05/15)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/05/15)
@nl
наукова стаття, опублікована в травні 2007
@uk
مقالة علمية (نشرت في 15-5-2007)
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name
Nucleotide receptor signaling ...... tive oxygen species generation
@ast
Nucleotide receptor signaling ...... tive oxygen species generation
@en
Nucleotide receptor signaling ...... tive oxygen species generation
@nl
type
label
Nucleotide receptor signaling ...... tive oxygen species generation
@ast
Nucleotide receptor signaling ...... tive oxygen species generation
@en
Nucleotide receptor signaling ...... tive oxygen species generation
@nl
prefLabel
Nucleotide receptor signaling ...... tive oxygen species generation
@ast
Nucleotide receptor signaling ...... tive oxygen species generation
@en
Nucleotide receptor signaling ...... tive oxygen species generation
@nl
P2093
P2860
P1476
Nucleotide receptor signaling ...... tive oxygen species generation
@en
P2093
Alma N. Guerra
David J. Hall
Lindsay M. Hill
Monica L. Gavala
Paul J. Bertics
Usha Prabhu
Zachary A. Pfeiffer
P2860
P304
P356
10.1016/J.FREERADBIOMED.2007.02.010
P577
2007-05-15T00:00:00Z