Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells
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Ursolic acid-mediated apoptosis of K562 cells involves Stat5/Akt pathway inhibition through the induction of Gfi-1Ursolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells.In Vitro Antiproliferative Activity of Extracts of Carlina acaulis subsp. caulescens and Carlina acanthifolia subsp. utzkaUse of dietary phytochemicals to target inflammation, fibrosis, proliferation, and angiogenesis in uterine tissues: promising options for prevention and treatment of uterine fibroids?Ursolic acid induces cell cycle arrest and apoptosis of gallbladder carcinoma cells.Evolution in medicinal chemistry of ursolic acid derivatives as anticancer agentsExtending in silico mechanism-of-action analysis by annotating targets with pathways: application to cellular cytotoxicity readouts.Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells.Ursolic acid suppresses leptin-induced cell proliferation in rat vascular smooth muscle cells.Matrix metalloproteinase-9 overexpression is closely related to poor prognosis in patients with colon cancer.Ursolic acid, a natural pentacyclic triterpenoid, inhibits intracellular trafficking of proteins and induces accumulation of intercellular adhesion molecule-1 linked to high-mannose-type glycans in the endoplasmic reticulum.Ursolic acid triggers nonprogrammed death (necrosis) in human glioblastoma multiforme DBTRG-05MG cells through MPT pore opening and ATP decline.Potential use of nanocarriers with pentacyclic triterpenes in cancer treatments.The synergistic biologic activity of oleanolic and ursolic acids in complex with hydroxypropyl-γ-cyclodextrin.Rosmarinic acid potentiates carnosic acid induced apoptosis in lung fibroblasts.Ursolic acid ameliorates autoimmune arthritis via suppression of Th17 and B cell differentiation.Si Shen Wan Inhibits mRNA Expression of Apoptosis-Related Molecules in p38 MAPK Signal Pathway in Mice with Colitis.Ursolic acid inhibited growth of hepatocellular carcinoma HepG2 cells through AMPKα-mediated reduction of DNA methyltransferase 1.Cardamonin reduces chemotherapy resistance of colon cancer cells via the TSP50/NF-κB pathway in vitro.
P2860
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P2860
Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells
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2013 nî lūn-bûn
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2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@ast
Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@en
Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@nl
type
label
Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@ast
Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@en
Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@nl
prefLabel
Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@ast
Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@en
Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@nl
P2093
P2860
P3181
P1433
P1476
Ursolic acid simultaneously ta ...... poptosis in colon cancer cells
@en
P2093
Dingbo Shi
Huijuan Qiu
Jianding Cheng
Jingshu Wang
Wangbing Chen
Wenlin Huang
Wuguo Deng
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0063872
P407
P577
2013-01-01T00:00:00Z