Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis
about
LARP6 Meets Collagen mRNA: Specific Regulation of Type I Collagen ExpressionRole of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane.Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen.Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNACharacterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs: implications for synthesis of type I collagenLa-related protein 6 controls ciliated cell differentiation.Upregulated expression of La ribonucleoprotein domain family member 6 and collagen type I gene following water-filtered broad-spectrum near-infrared irradiation in a 3-dimensional human epidermal tissue culture model as revealed by microarray analysLong-term administration of tacrolimus and everolimus prevents high cholesterol-high fructose-induced steatosis in C57BL/6J mice by inhibiting de-novo lipogenesis.
P2860
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P2860
Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
@ast
Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
@en
Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
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type
label
Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
@ast
Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
@en
Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
@nl
prefLabel
Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
@ast
Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
@en
Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
@nl
P2093
P2860
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Tacrolimus (FK506) prevents ea ...... echanism of collagen synthesis
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P2093
Branko Stefanovic
John Blackmon
Zarko Manojlovic
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P304
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P356
10.1371/JOURNAL.PONE.0065897
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2013-01-01T00:00:00Z