Improving pharmacokinetic-pharmacodynamic modeling to investigate anti-infective chemotherapy with application to the current generation of antimalarial drugs

Improving pharmacokinetic-pharmacodynamic modeling to investigate anti-infective chemotherapy with application to the current generation of antimalarial drugs

Item
http://www.wikidata.org/entity/Q28534701
Making the most of clinical data: reviewing the role of pharmacokinetic-pharmacodynamic models of anti-malarial drugsMathematical Modelling to Guide Drug Development for Malaria EliminationOptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimensOptimizing the programmatic deployment of the anti-malarials artemether-lumefantrine and dihydroartemisinin-piperaquine using pharmacological modelling.Measuring windows of selection for anti-malarial drug treatments.Rethinking Dosing Regimen Selection of Piperaquine for Malaria Chemoprevention: A Simulation Study.Altering Antimalarial Drug Regimens May Dramatically Enhance and Restore Drug Effectiveness.How Robust Are Malaria Parasite Clearance Rates as Indicators of Drug Effectiveness and Resistance?Incorporating Stage-Specific Drug Action into Pharmacological Modeling of Antimalarial Drug TreatmentQuantifying the pharmacology of antimalarial drug combination therapy.Modeling within-host effects of drugs on Plasmodium falciparum transmission and prospects for malaria elimination.Pharmacological considerations in the design of anti-malarial drug combination therapies - is matching half-lives enough?Improving the role and contribution of pharmacokinetic analyses in antimalarial drug clinical trials.Use of quantitative pharmacology tools to improve malaria treatments.Split dosing of artemisinins does not improve antimalarial therapeutic efficacyAssessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling.A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum.
P2860

Improving pharmacokinetic-pharmacodynamic modeling to investigate anti-infective chemotherapy with application to the current generation of antimalarial drugs

Item
http://www.wikidata.org/entity/Q28534701
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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Improving pharmacokinetic-phar ...... neration of antimalarial drugs
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10.1371/JOURNAL.PCBI.1003151
P407
P433
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P50
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P932