Immunomodulatory effects in a phase II study of lenalidomide combined with cetuximab in refractory KRAS-mutant metastatic colorectal cancer patients
about
Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).Chemical approaches to targeted protein degradation through modulation of the ubiquitin-proteasome pathwayLenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activityAnti-EGFR MoAb treatment in colorectal cancer: limitations, controversies, and contradictories.Synthesis and biological evaluation of santacruzamate A analogues for anti-proliferative and immunomodulatory activity.Immunomodulatory Drugs in Multiple Myeloma: Mechanisms of Action and Clinical Experience.Metabolic Hallmarks of Tumor and Immune Cells in the Tumor MicroenvironmentPhase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients.Systemic inflammatory status predict the outcome of k-RAS WT metastatic colorectal cancer patients receiving the thymidylate synthase poly-epitope-peptide anticancer vaccine.
P2860
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P2860
Immunomodulatory effects in a phase II study of lenalidomide combined with cetuximab in refractory KRAS-mutant metastatic colorectal cancer patients
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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name
Immunomodulatory effects in a ...... tic colorectal cancer patients
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Immunomodulatory effects in a ...... tic colorectal cancer patients
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Immunomodulatory effects in a ...... tic colorectal cancer patients
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type
label
Immunomodulatory effects in a ...... tic colorectal cancer patients
@ast
Immunomodulatory effects in a ...... tic colorectal cancer patients
@en
Immunomodulatory effects in a ...... tic colorectal cancer patients
@nl
prefLabel
Immunomodulatory effects in a ...... tic colorectal cancer patients
@ast
Immunomodulatory effects in a ...... tic colorectal cancer patients
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Immunomodulatory effects in a ...... tic colorectal cancer patients
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P2093
P2860
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Immunomodulatory effects in a ...... tic colorectal cancer patients
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P2093
Alfredo Romano
Anita K Gandhi
Peter H Schafer
Rajesh Chopra
Ulf Jungnelius
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0080437
P407
P577
2013-01-01T00:00:00Z