A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
about
Transcription by RNA polymerase III: insights into mechanism and regulationModify or die?--RNA modification defects in metazoansDifferent types of secondary information in the genetic code.High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA-tRNA interfaceChromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle.Unbiased Quantitative Models of Protein Translation Derived from Ribosome Profiling Data.Codon-Driven Translational Efficiency Is Stable across Diverse Mammalian Cell States.Tissue- and Time-Specific Expression of Otherwise Identical tRNA GenesHigh-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations.Large-Effect Beneficial Synonymous Mutations Mediate Rapid and Parallel Adaptation in a Bacterium.Decoding the principles underlying the frequency of association with nucleoli for RNA polymerase III-transcribed genes in budding yeast.tRNA genes rapidly change in evolution to meet novel translational demands.Factors That Shape Eukaryotic tRNAomes: Processing, Modification and Anticodon-Codon Use.Synonymous codons, ribosome speed, and eukaryotic gene expression regulation.Emerging roles of tRNA in adaptive translation, signalling dynamics and disease.A resource for functional profiling of noncoding RNA in the yeast Saccharomyces cerevisiae.The Fungus Candida albicans Tolerates Ambiguity at Multiple Codons.The fitness landscape of a tRNA gene.Synthetic genome recoding: new genetic codes for new features.Identification of the mRNA targets of tRNA-specific regulation using genome-wide simulation of translationMaximizing protein translation rate in the non-homogeneous ribosome flow model: a convex optimization approach.Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome.Diversity of translation initiation mechanisms across bacterial species is driven by environmental conditions and growth demands.Generation of an arginine-tRNA-adapted Saccharomyces cerevisiae strain for effective heterologous protein expression.Codon choice directs constitutive mRNA levels in trypanosomes.Large-scale profiling of noncoding RNA function in yeast.Pooled CRISPR interference screening enables genome-scale functional genomics study in bacteria with superior performance.Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditionsTransfer RNA genes experience exceptionally elevated mutation rates
P2860
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P2860
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
description
2014 nî lūn-bûn
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2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@ast
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@en
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@nl
type
label
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@ast
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@en
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@nl
prefLabel
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@ast
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@en
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@nl
P2093
P2860
P3181
P1433
P1476
A comprehensive tRNA deletion library unravels the genetic architecture of the tRNA pool
@en
P2093
Hila Gingold
Orna Dahan
Ruth Towers
Sivan Navon
Yitzhak Pilpel
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1004084
P407
P577
2014-01-01T00:00:00Z