A chaperone-assisted degradation pathway targets kinetochore proteins to ensure genome stability
about
Protein quality control in the nucleusDistinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.How the nucleus copes with proteotoxic stress.Control of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1LSingle site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing.Hsp70 clears misfolded kinases that partitioned into distinct quality-control compartments.A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission YeastPredicting the impact of Lynch syndrome-causing missense mutations from structural calculationsChaperoning proteins for destruction: diverse roles of Hsp70 chaperones and their co-chaperones in targeting misfolded proteins to the proteasomeBioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases.UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1.The ClpS-like N-domain is essential for the functioning of Ubr11, an N-recognin in Schizosaccharomyces pombe.Emerging Paradigm of Crosstalk between Autophagy and the Ubiquitin-Proteasome System.Proteome Stability as a Key Factor of Genome Integrity.The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components.Blocking protein quality control to counter hereditary cancers.The exocyst subunit Sec3 is regulated by a protein quality control pathway.
P2860
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P2860
A chaperone-assisted degradation pathway targets kinetochore proteins to ensure genome stability
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A chaperone-assisted degradati ...... ins to ensure genome stability
@ast
A chaperone-assisted degradati ...... ins to ensure genome stability
@en
A chaperone-assisted degradati ...... ins to ensure genome stability
@nl
type
label
A chaperone-assisted degradati ...... ins to ensure genome stability
@ast
A chaperone-assisted degradati ...... ins to ensure genome stability
@en
A chaperone-assisted degradati ...... ins to ensure genome stability
@nl
prefLabel
A chaperone-assisted degradati ...... ins to ensure genome stability
@ast
A chaperone-assisted degradati ...... ins to ensure genome stability
@en
A chaperone-assisted degradati ...... ins to ensure genome stability
@nl
P2093
P2860
P1433
P1476
A chaperone-assisted degradati ...... ins to ensure genome stability
@en
P2093
Assen Roguev
Colin Gordon
Esben G Poulsen
Franziska Kriegenburg
Nevan Krogan
Sofie Vincents Nielsen
Ursula Fleig
Visnja Jakopec
P2860
P304
P356
10.1371/JOURNAL.PGEN.1004140
P407
P577
2014-01-30T00:00:00Z