A mechanistic tumor penetration model to guide antibody drug conjugate design

A mechanistic tumor penetration model to guide antibody drug conjugate design

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http://www.wikidata.org/entity/Q28544636
Sacituzumab govitecan (IMMU-132), an anti-Trop-2-SN-38 antibody-drug conjugate for the treatment of diverse epithelial cancers: Safety and pharmacokinetics.Selective Tumor Targeting of Desacetyl Vinblastine Hydrazide and Tubulysin B via Conjugation to a Cholecystokinin 2 Receptor (CCK2R) LigandMultiscale Modeling of Antibody-Drug Conjugates: Connecting Tissue and Cellular Distribution to Whole Animal Pharmacokinetics and Potential Implications for Efficacy.Prospects and progress of antibody-drug conjugates in solid tumor therapies.AFIR: A Dimensionless Potency Metric for Characterizing the Activity of Monoclonal Antibodies.Paradigm shift in bacteriophage-mediated delivery of anticancer drugs: from targeted 'magic bullets' to self-navigated 'magic missiles'.Antibody-Drug Conjugates as Cancer Therapeutics: Past, Present, and Future.Pharmacokinetic Considerations for Antibody-Drug Conjugates against Cancer.A novel individual-cell-based mathematical model based on multicellular tumour spheroids for evaluating doxorubicin-related delivery in avascular regions.Transport of drugs from blood vessels to tumour tissue.DNA damaging agent-based antibody-drug conjugates for cancer therapy
P2860

A mechanistic tumor penetration model to guide antibody drug conjugate design

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http://www.wikidata.org/entity/Q28544636
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2015 nî lūn-bûn
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2015 թուականին հրատարակուած գիտական յօդուած
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2015 թվականին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
A mechanistic tumor penetration model to guide antibody drug conjugate design
@ast
A mechanistic tumor penetration model to guide antibody drug conjugate design
@en
A mechanistic tumor penetration model to guide antibody drug conjugate design
@nl
type
label
A mechanistic tumor penetration model to guide antibody drug conjugate design
@ast
A mechanistic tumor penetration model to guide antibody drug conjugate design
@en
A mechanistic tumor penetration model to guide antibody drug conjugate design
@nl
prefLabel
A mechanistic tumor penetration model to guide antibody drug conjugate design
@ast
A mechanistic tumor penetration model to guide antibody drug conjugate design
@en
A mechanistic tumor penetration model to guide antibody drug conjugate design
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
A mechanistic tumor penetration model to guide antibody drug conjugate design
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0118977
P407
P433
P478
P577
P5875
P698
P921
P932