Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism

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Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism

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2016 nî lūn-bûn

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2016 թուականին հրատարակուած գիտական յօդուած

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2016 թվականին հրատարակված գիտական հոդված

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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name

Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

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Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

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Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

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type

Item

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Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

@ast

Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

@en

Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

@nl

prefLabel

Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

@ast

Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

@en

Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

@nl

P1476

Pathophysiological Consequence ...... by S1P1 Competitive Antagonism

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P2093

Birgit Bollbuck

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Christian Beerli

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Christian Bruns

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Daniela Angst

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Elisabeth Rosner

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Gina Fishli-Cavelti

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Heike Otto

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Janet Dawson

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Jean Quancard

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Marc Bigaud

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P2860

Tonic regulation of vascular permeability

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Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

Second generation S1P pathway modulators: research strategies and clinical developments.

The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1.

Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.

Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury.

An oral sphingosine 1-phosphate receptor 1 (S1P(1)) antagonist prodrug with efficacy in vivo: discovery, synthesis, and evaluation.

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.

P304

e0168252

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scholarly article

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10.1371/JOURNAL.PONE.0168252

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P407

English

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P478

http://www.w3.org/2001/XMLSchema#string

P577

2016-01-01T00:00:00Z

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P698

28005953

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P921

pathophysiology

P932

5179015

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