Selective interactions between Gi alpha1 and Gi alpha3 and the GoLoco/GPR domain of RGS14 influence its dynamic subcellular localization
about
Localization of Gi alpha proteins in the centrosomes and at the midbody: implication for their role in cell division.RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory.RGS14 at the interface of hippocampal signaling and synaptic plasticityRGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathwaysActivation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8ARegulator of G-protein signaling 14 (RGS14) is a selective H-Ras effectorNon-canonical functions of RGS proteinsIdentification of transcription factor E3 (TFE3) as a receptor-independent activator of Gα16: gene regulation by nuclear Gα subunit and its activator.G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifsG protein-coupled receptors and resistance to inhibitors of cholinesterase-8A (Ric-8A) both regulate the regulator of g protein signaling 14 RGS14·Gαi1 complex in live cellsIntegration of G protein α (Gα) signaling by the regulator of G protein signaling 14 (RGS14).Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling.A finer tuning of G-protein signaling through regulated control of RGS proteins.Roles for Regulator of G Protein Signaling Proteins in Synaptic Signaling and Plasticity.Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors.The Ras-binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins.Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain.Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif.Regulator of G protein signaling 14 (RGS14) is expressed pre- and postsynaptically in neurons of hippocampus, basal ganglia, and amygdala of monkey and human brain.RGS14 regulates the lifetime of Gα-GTP signaling but does not prolong Gβγ signaling following receptor activation in live cells.Endogenous RGS14 is a cytoplasmic-nuclear shuttling protein that localizes to juxtanuclear membranes and chromatin-rich regions of the nucleusG protein coupled receptor signaling complexes in live cells.The importance of N-terminal polycysteine and polybasic sequences for G14alpha and G16alpha palmitoylation, plasma membrane localization, and signaling function.Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease
P2860
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P2860
Selective interactions between Gi alpha1 and Gi alpha3 and the GoLoco/GPR domain of RGS14 influence its dynamic subcellular localization
description
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
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im Januar 2007 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2007/01/01)
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vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/01/01)
@nl
наукова стаття, опублікована в січні 2007
@uk
مقالة علمية (نشرت عام 2007)
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name
Selective interactions between ...... namic subcellular localization
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Selective interactions between ...... namic subcellular localization
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Selective interactions between ...... namic subcellular localization
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type
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Selective interactions between ...... namic subcellular localization
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Selective interactions between ...... namic subcellular localization
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Selective interactions between ...... namic subcellular localization
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prefLabel
Selective interactions between ...... namic subcellular localization
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Selective interactions between ...... namic subcellular localization
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Selective interactions between ...... namic subcellular localization
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P2093
P3181
P1433
P1476
Selective interactions between ...... namic subcellular localization
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P2093
Feng-jue Shu
John R. Hepler
Suneela Ramineni
Whitney Amyot
P304
P3181
P356
10.1016/J.CELLSIG.2006.06.002
P577
2007-01-01T00:00:00Z