Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures
about
Kainate receptors coming of age: milestones of two decades of researchPathology and pathophysiology of the amygdala in epileptogenesis and epilepsyRole of nucleus accumbens glutamatergic plasticity in drug addictionBinding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonistsRole of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesisThe neurobiology of antiepileptic drugsIncreased anxiety-like behavior and enhanced synaptic efficacy in the amygdala of GluR5 knockout miceThe limitations of diazepam as a treatment for nerve agent-induced seizures and neuropathology in rats: comparison with UBP302.Presynaptic facilitation of glutamate release in the basolateral amygdala: a mechanism for the anxiogenic and seizurogenic function of GluK1 receptors.Increased sensitivity to kainic acid in a genetic model of reduced NMDA receptor function.Target-cell specificity of kainate autoreceptor and Ca2+-store-dependent short-term plasticity at hippocampal mossy fiber synapses.Novel analogs and stereoisomers of the marine toxin neodysiherbaine with specificity for kainate receptorsDifferential regulation of kainate receptor trafficking by phosphorylation of distinct sites on GluR6.Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine.Ligands for ionotropic glutamate receptorsDifferential contribution of kainate receptors to excitatory postsynaptic currents in superficial layer neurons of the rat medial entorhinal cortex.Soman induces ictogenesis in the amygdala and interictal activity in the hippocampus that are blocked by a GluR5 kainate receptor antagonist in vitroThe GluK1 (GluR5) Kainate/{alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist LY293558 reduces soman-induced seizures and neuropathology.Muscarinic excitation of parvalbumin-positive interneurons contributes to the severity of pilocarpine-induced seizures.Kainate receptors and the induction of mossy fibre long-term potentiation.Piperazine-2,3-dicarboxylic acid derivatives as dual antagonists of NMDA and GluK1-containing kainate receptorsPhysiology and pathology of calcium signaling in the brain.A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonistsTherapeutic potential of kainate receptors.Efficacy of the GluK1/AMPA receptor antagonist LY293558 against seizures and neuropathology in a soman-exposure model without pretreatment and its pharmacokinetics after intramuscular administrationIonotropic glutamate receptors & CNS disorders.Pathological alterations in GABAergic interneurons and reduced tonic inhibition in the basolateral amygdala during epileptogenesis.Primary brain targets of nerve agents: the role of the amygdala in comparison to the hippocampus.Medicinal chemistry of competitive kainate receptor antagonists.Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonistsKainate receptor-induced ectopic spiking of CA3 pyramidal neurons initiates network bursts in neonatal hippocampus.Subunit-specific desensitization of heteromeric kainate receptors.GABAergic inhibition shapes interictal dynamics in awake epileptic mice.Comparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric Population.Kainate Receptors: Role in Epilepsy.
P2860
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P2860
Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im August 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/08/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/08/01)
@nl
наукова стаття, опублікована в серпні 2002
@uk
مقالة علمية (نشرت في أغسطس 2002)
@ar
name
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@ast
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@en
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@nl
type
label
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@ast
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@en
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@nl
prefLabel
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@ast
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@en
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@nl
P2093
P356
P1433
P1476
Antagonists of GLU(K5)-contain ...... arpine-induced limbic seizures
@en
P2093
AnnMarie Ogden
Brianne Weiss
David Bleakman
David Lodge
Ghous M Khan
Graham L Collingridge
Guy Ebinger
Ilse Smolders
James P Stables
P2888
P304
P356
10.1038/NN880
P407
P577
2002-08-01T00:00:00Z