The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypert
about
Helix-loop-helix protein p8, a transcriptional regulator required for cardiomyocyte hypertrophy and cardiac fibroblast matrix metalloprotease inductionFunctional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1Stress-inducible protein p8 is involved in several physiological and pathological processes.Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function.From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypesDecreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8.Expression and roles of NUPR1 in cholangiocarcinoma cellsLeptin induces rat glomerular mesangial cell hypertrophy, but does not regulate hyperplasia or apoptosis.p8 expression controls pancreatic cancer cell migration, invasion, adhesion, and tumorigenesis.p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage.Platelet-derived growth factor BB induces nuclear export and proteasomal degradation of CREB via phosphatidylinositol 3-kinase/Akt signaling in pulmonary artery smooth muscle cells.Developmentally regulated synthesis of p8, a stress-associated transcription cofactor, in diapause-destined embryos of Artemia franciscana.Nupr1 deletion protects against glucose intolerance by increasing beta cell mass.Identification of a mitochondrial defect gene signature reveals NUPR1 as a key regulator of liver cancer progression.1,4-Dihydropyridine derivatives without Ca2+-antagonist activity up-regulate Psma6 mRNA expression in kidneys of intact and diabetic rats.
P2860
Q24673841-86B38858-04B6-4E68-9135-71D7097972E2Q28115653-419DC178-21EA-4869-B204-56BBDC66C5FFQ33581809-0BCE8C06-C1F1-45B3-9FA2-484ACBA0F5D6Q33787246-9DF211A9-DC1F-4F9A-A846-719821F6B01FQ34482996-08D51D2D-4EA9-4B3C-B414-3D422645A13BQ35543254-436E8B56-1652-49F6-BB24-6B6954745739Q35895202-C50770D2-5B4E-4DDE-A3AC-75DC67E044DEQ38324028-30A183E3-7F80-4A5A-9B0F-ED4ECFA5E4AAQ39587471-D3E76A55-EF4D-4FD8-B5ED-BF1DD5190AD7Q39817713-8F96DF23-B3C0-4439-A417-0C16EAF5218AQ41491090-E24588D2-3EC0-4C5C-A160-6BD8624C73E1Q42384708-84F700D7-E977-4561-93F6-8EBD6F6811F5Q42442347-0C018F8F-B2C9-49CA-8F51-4870E84A6E16Q51612952-1AB444E9-E976-4BA4-AC98-F266C9425EA8Q53393393-00F48922-EB40-4CCF-86D8-1348F1F2270D
P2860
The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypert
description
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im Mai 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/05/14)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/05/14)
@nl
наукова стаття, опублікована в травні 2004
@uk
name
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@ast
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@en
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@nl
type
label
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@ast
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@en
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@nl
prefLabel
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@ast
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@en
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@nl
P2860
P356
P1476
The pro-hypertrophic basic hel ...... nd renal mesangial cell hypert
@en
P2093
John M. Kyriakis
Sandro Goruppi
P2860
P304
20950–20958
P356
10.1074/JBC.M312401200
P407
P577
2004-05-14T00:00:00Z