Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity
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The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of MyofibroblastsRole of redoximiRs in fibrogenesisReciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosisRedox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequencesRole of NADPH oxidases in the redox biology of liver fibrosisPrimary hepatocytes and their cultures in liver apoptosis researchImplications of biomarkers in human hepatocellular carcinoma pathogenesis and therapyOxidative stress and pulmonary fibrosisReactive oxygen species and fibrosis: further evidence of a significant liaisonDisruptive environmental chemicals and cellular mechanisms that confer resistance to cell deathPolyenephosphatidylcholine prevents alcoholic liver disease in PPARalpha-null mice through attenuation of increases in oxidative stressNox4 and redox signaling mediate TGF-β-induced endothelial cell apoptosis and phenotypic switchOxidative stress and glutathione in TGF-beta-mediated fibrogenesisCRISPR-Cas9 Mediated NOX4 Knockout Inhibits Cell Proliferation and Invasion in HeLa CellsThe liver-specific tumor suppressor STAT5 controls expression of the reactive oxygen species-generating enzyme NOX4 and the proapoptotic proteins PUMA and BIM in mice.Nox4-generated superoxide drives angiotensin II-induced neural stem cell proliferation.Role of NADPH oxidases in liver fibrosis.European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).Decoding NADPH oxidase 4 expression in human tumors.Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor beta1-induced expression of plasminogen activator inhibitor 1 in fibroblasts.4-O-Methylhonokiol Protects HaCaT Cells from TGF-β1-Induced Cell Cycle Arrest by Regulating Canonical and Non-Canonical Pathways of TGF-β SignalingOxidative stress and hepatic Nox proteins in chronic hepatitis C and hepatocellular carcinoma.Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17.Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo.NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.Mouse hepatic oval cells require Met-dependent PI3K to impair TGF-β-induced oxidative stress and apoptosis.Distinctive pharmacological differences between liver cancer cell lines HepG2 and Hep3B.DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma.Mechanisms linking obesity, chronic kidney disease, and fatty liver disease: the roles of fetuin-A, adiponectin, and AMPK.Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice.How do cytokines trigger genomic instability?Overexpression of engulfment and cell motility 1 promotes cell invasion and migration of hepatocellular carcinoma.Transforming growth factor-β, bioenergetics, and mitochondria in renal diseaseExcess TGF-β mediates muscle weakness associated with bone metastases in mice.Lung extracellular matrix and redox regulationNADPH oxidase biology and the regulation of tyrosine kinase receptor signaling and cancer drug cytotoxicityOxidative stress mediates radiation lung injury by inducing apoptosis.Uric acid and transforming growth factor in fructose-induced production of reactive oxygen species in skeletal muscleInhibiting TGFβ1 has a protective effect on mouse bone marrow suppression following ionizing radiation exposure in vitroIntrahepatic microcirculatory disorder, parenchymal hypoxia and NOX4 upregulation result in zonal differences in hepatocyte apoptosis following lipopolysaccharide- and D-galactosamine-induced acute liver failure in rats.
P2860
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P2860
Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity
description
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Dezember 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/12/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/12/01)
@nl
наукова стаття, опублікована в грудні 2008
@uk
مقالة علمية (نشرت في ديسمبر 2008)
@ar
name
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@ast
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@en
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@nl
type
label
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@ast
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@en
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@nl
prefLabel
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@ast
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@en
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@nl
P2093
P50
P3181
P1476
Upregulation of the NADPH oxid ...... for its pro-apoptotic activity
@en
P2093
César Roncero
Irene Carmona-Cuenca
Nelson Fausto
P304
P3181
P356
10.1016/J.JHEP.2008.07.021
P577
2008-12-01T00:00:00Z