Prostaglandin receptor subtypes, EP3C and EP4, mediate the prostaglandin E2-induced cAMP production and sensitization of sensory neurons
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Antinociceptive activity of the ethanolic extract, fractions, and aggregatin D isolated from Sinningia aggregata tubersPeripheral sensitization increases opioid receptor expression and activation by crotalphine in ratsCharacterization of the prostanoid receptor types involved in mediating calcitonin gene-related peptide release from cultured rat trigeminal neuronesProlonged aspirin inhibition of anodal vasodilation is not due to the trafficking delay of neural mediatorsActivation of EP4 receptors contributes to prostaglandin E2-mediated stimulation of renal sensory nervesProstaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblastsA Ser/Thr cluster within the C-terminal domain of the rat prostaglandin receptor EP3alpha is essential for agonist-induced phosphorylation, desensitization and internalizationNerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to Epac[EXPRESS] Epac and Nociceptor Sensitization.Sustained morphine treatment augments prostaglandin E2-evoked calcitonin gene-related peptide release from primary sensory neurons in a PKA-dependent manner.Bradykinin and prostaglandin E₁ regulate calcitonin gene-related peptide expression in cultured rat sensory neurons.Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasionSensory neurone responses to mucosal noxae in the upper gut: relevance to mucosal integrity and gastrointestinal pain.Expression of E-series prostaglandin (EP) receptors and urodynamic effects of an EP4 receptor antagonist on cyclophosphamide-induced overactive bladder in ratsAntinociceptive effect of tetrandrine on LPS-induced hyperalgesia via the inhibition of IKKβ phosphorylation and the COX-2/PGE₂ pathway in mice.The pharmacological effect of BGC20-1531, a novel prostanoid EP4 receptor antagonist, in the prostaglandin E2 human model of headache.Gastrointestinal pain in functional bowel disorders: sensory neurons as novel drug targets.Role played by interleukin-6 in evoking the exercise pressor reflex in decerebrate rats: effect of femoral artery ligation.Expression of prostaglandin I2 (prostacyclin) receptor in blood of migraine patients: A potential biomarkerAntihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neuronsRole of neurogenic inflammation in pancreatitis and pancreatic pain.Combined, but not individual, blockade of ASIC3, P2X, and EP4 receptors attenuates the exercise pressor reflex in rats with freely perfused hindlimb musclesThe prostaglandin E2 receptor, EP2, is upregulated in the dorsal root ganglion after painful cervical facet joint injury in the rat.Epac activation sensitizes rat sensory neurons through activation of Ras.Synergistic depression of NMDA receptor-mediated transmission by ketamine, ketoprofen and L-NAME combinations in neonatal rat spinal cords in vitro.Scaffolding by A-kinase anchoring protein enhances functional coupling between adenylyl cyclase and TRPV1 channel.The mechano-gated channel inhibitor GsMTx4 reduces the exercise pressor reflex in rats with ligated femoral arteries.Long-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A.Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons.BGC20-1531, a novel, potent and selective prostanoid EP receptor antagonist: a putative new treatment for migraine headache.Peripheral mechanisms of pain and analgesia.Activation of calcitonin gene-related peptide signaling through the prostaglandin E2-EP1/EP2/EP4 receptor pathway in synovium of knee osteoarthritis patients.Targeting pain mediators induced by injured nerve-derived COX2 and PGE2 to treat neuropathic pain.Extracellular matrix fibronectin increases prostaglandin E2 receptor subtype EP4 in lung carcinoma cells through multiple signaling pathways: the role of AP-2.Activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) increases the expression of prostaglandin E2 receptor subtype EP4. The roles of phosphatidylinositol 3-kinase and CCAAT/enhancer-binding protein beta.The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons.The action of prostaglandins on ion channels.Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway.Intraplantar PGE2 causes nociceptive behaviour and mechanical allodynia: the role of prostanoid E receptors and protein kinases.
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P2860
Prostaglandin receptor subtypes, EP3C and EP4, mediate the prostaglandin E2-induced cAMP production and sensitization of sensory neurons
description
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Mai 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/05/11)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/05/11)
@nl
наукова стаття, опублікована в травні 2001
@uk
name
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@ast
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@en
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@nl
type
label
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@ast
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@en
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@nl
prefLabel
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@ast
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@en
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@nl
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P921
P3181
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P1476
Prostaglandin receptor subtype ...... nsitization of sensory neurons
@en
P2093
M. D. Southall
M. R. Vasko
P2860
P304
16083–16091
P3181
P356
10.1074/JBC.M011408200
P407
P577
2001-05-11T00:00:00Z