Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
about
Nonmuscle myosin-2: mix and matchTubby and tubby-like protein 1 are new MerTK ligands for phagocytosisCircadian and noncircadian modulation of autophagy in photoreceptors and retinal pigment epithelium.Phagocytosis of retinal rod and cone photoreceptors.Increased expression of Mer tyrosine kinase in circulating dendritic cells and monocytes of lupus patients: correlations with plasma interferon activity and steroid therapy.The retinal pigment epithelium in health and diseaseUnderstanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture.Unraveling the molecular mystery of retinal pigment epithelium phagocytosis.mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice.MERTK interactions with SH2-domain proteins in the retinal pigment epithelium.Generation of Cre transgenic mice with postnatal RPE-specific ocular expressionLarge-scale purification of porcine or bovine photoreceptor outer segments for phagocytosis assays on retinal pigment epithelial cells.Mertk deficiency affects macrophage directional migration via disruption of cytoskeletal organization.MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors.Mertk deficiency alters expression of micrornas in the retinal pigment epithelium cellsEssential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinaseHuman iPSC derived disease model of MERTK-associated retinitis pigmentosaLeukemia inhibitory factor coordinates the down-regulation of the visual cycle in the retina and retinal-pigmented epithelium.Regulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium Is Essential for Vision.A chimerical phagocytosis model reveals the recruitment by Sertoli cells of autophagy for the degradation of ingested illegitimate substratesBiology of the TAM receptors.p27(KIP1) loss promotes proliferation and phagocytosis but prevents epithelial-mesenchymal transition in RPE cells after photoreceptor damage.Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme.Tubby regulates microglial phagocytosis through MerTK.PI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells.Focus on molecules: MERTK.Human umbilical tissue-derived cells rescue retinal pigment epithelium dysfunction in retinal degeneration.P2X7 receptors mediate innate phagocytosis by human neural precursor cells and neuroblasts.RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells.CCDC102B confers risk of low vision and blindness in high myopia.Advanced molecular approaches pave the road to a clear-cut diagnosis of hereditary retinal dystrophies
P2860
Q27022727-6017DE8B-D752-4A8D-B828-BC88D6099FA9Q28513697-1FC1EA69-199A-443C-8C47-DB3395A48F5BQ33683462-E12522D7-B0CB-402F-8468-872D7DC7DB4DQ33731918-ED922432-44BE-4F5C-8819-B66D7AE450C1Q33765614-96D28149-1693-4001-A0BB-51BE72310DB7Q33998365-86D40559-30D8-4ED6-809E-9351971EB05AQ34090518-2F6FA15E-B49D-47AB-B3B9-D648F64A48BAQ34106171-D407CCA4-C088-4574-8864-DC68B834FD2DQ34429001-2CE345C3-14D5-495C-A589-1904EA266AF2Q34579894-3D3C800C-A182-41FB-984B-D4E0F412B934Q35005840-5F3789B4-AD40-4C83-9655-BEA7C4BE5D5FQ35415339-900E66AE-E139-4888-BAC6-DC023C9C1C53Q35548612-61D50C9C-A68B-4E61-8158-6F205A1714D5Q35748292-03BC2660-9E49-4991-8E64-59D090CEB929Q35822779-F51873D3-E6EC-49B5-9C10-E02E4671C14BQ35827514-3543FDA6-DEB1-45BD-8FBD-0F0D13C1E741Q35937882-B16C5A1F-555C-403B-AA14-1957CE5B84D3Q36097895-2A73BF3F-6242-47CE-9177-A68041DFA18DQ36744774-12BE8FA8-CD70-464D-86D9-C9E5914DF4B7Q36892063-73646480-9621-4FEE-BDC8-20BD280B8D0DQ37258717-CF3C9AD2-2A06-4506-9734-5D4D54607DDDQ37292705-6162AA18-D7AA-4F9D-AF29-0D147AF3B6A3Q39370401-E5FCD1E1-0921-4252-A9A6-E739B5DA4D4BQ41851143-23314069-F479-4153-B5C5-439E4D510858Q42256993-E737F7FD-D19F-4465-894C-F4B4D448BF27Q42794383-FD512504-34CB-4CC5-B49E-47326101FEB6Q46651920-B9ED1D18-525C-4AFD-9986-F562B9DCC606Q48478445-A614A186-82B1-4B2C-ACC7-76E76C665736Q52657629-9961E29E-99F5-4B4D-97C9-339C3001D41EQ55387267-84B31BFC-90A2-459E-B1E8-19DE704B6D3EQ58721156-6FA251C1-AB65-48ED-8280-659055088DE5
P2860
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
description
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Mai 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/05/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/05/01)
@nl
наукова стаття, опублікована в травні 2009
@uk
مقالة علمية (نشرت في مايو 2009)
@ar
name
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@ast
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@en
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@nl
type
label
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@ast
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@en
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@nl
prefLabel
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@ast
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@en
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@nl
P2093
P356
P1476
Mertk drives myosin II redistribution during retinal pigment epithelial phagocytosis
@en
P2093
David J. Strick
Douglas Vollrath
P304
P356
10.1167/IOVS.08-3058
P407
P577
2009-05-01T00:00:00Z