Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration
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Alterations in Mitochondrial Quality Control in Alzheimer's DiseaseMitochondria-associated membranes as hubs for neurodegenerationInner membrane fusion mediates spatial distribution of axonal mitochondriaAlterations of mitochondrial dynamics allow retrograde propagation of locally initiated axonal insultsEnergy failure: does it contribute to neurodegeneration?Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathwayAxon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicityMitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons.Alteration of fatty-acid-metabolizing enzymes affects mitochondrial form and function in hereditary spastic paraplegia.Preserve and protect: maintaining axons within functional circuits.Axonal Charcot-Marie-Tooth disease patient-derived motor neurons demonstrate disease-specific phenotypes including abnormal electrophysiological properties.Mitochondrial fission augments capsaicin-induced axonal degenerationWldS and PGC-1α regulate mitochondrial transport and oxidation state after axonal injuryAxons degenerate in the absence of mitochondria in C. elegansMitochondria: key players in the neurotoxic effects of amphetamines.Mitochondrial Fragmentation Due to Inhibition of Fusion Increases Cyclin B through Mitochondrial Superoxide RadicalsMechanism of Activation-Induced Downregulation of Mitofusin 2 in Human Peripheral Blood T CellsROS regulation of axonal mitochondrial transport is mediated by Ca2+ and JNK in DrosophilaCiliary neurotrophic factor activates NF-κB to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin-induced diabetic rodents.Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons.Mitochondrial morphology transitions and functions: implications for retrograde signaling?Sarm1-mediated axon degeneration requires both SAM and TIR interactionsDynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age.Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.Role of mitofusin 2 (Mfn2) in controlling cellular proliferation.Two novel compound heterozygous mutations in OPA3 in two siblings with OPA3-related 3-methylglutaconic aciduria.Deciphering the mechanism underlying late-onset Alzheimer disease.Curcumin, a potential therapeutic candidate for retinal diseases.Mitochondrial fusion proteins and human diseases.Recent advances in the genetic neuropathies.Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death.Mitochondrial fission and fusion in secondary brain damage after CNS insults.Mitochondrial dynamics in neuronal injury, development and plasticity.Characterization of the mitofusin 2 R94W mutation in a knock-in mouse model.Metabolic Vulnerability in the Neurodegenerative Disease Glaucoma.Mitochondrial Membrane Dynamics and Inherited Optic Neuropathies.Selective mitochondrial depletion, apoptosis resistance, and increased mitophagy in human Charcot-Marie-Tooth 2A motor neurons.L-3-n-Butylphthalide Protects HSPB8 K141N Mutation-Induced Oxidative Stress by Modulating the Mitochondrial Apoptotic and Nrf2 Pathways.NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease.A viral peptide that targets mitochondria protects against neuronal degeneration in models of Parkinson's disease.
P2860
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P2860
Mitofusin2 mutations disrupt axonal mitochondrial positioning and promote axon degeneration
description
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
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im März 2012 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2012/03/21)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/03/21)
@nl
наукова стаття, опублікована в березні 2012
@uk
مقالة علمية (نشرت في 21-3-2012)
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name
Mitofusin2 mutations disrupt a ...... and promote axon degeneration
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Mitofusin2 mutations disrupt a ...... and promote axon degeneration
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Mitofusin2 mutations disrupt a ...... and promote axon degeneration
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type
label
Mitofusin2 mutations disrupt a ...... and promote axon degeneration
@ast
Mitofusin2 mutations disrupt a ...... and promote axon degeneration
@en
Mitofusin2 mutations disrupt a ...... and promote axon degeneration
@nl
prefLabel
Mitofusin2 mutations disrupt a ...... and promote axon degeneration
@ast
Mitofusin2 mutations disrupt a ...... and promote axon degeneration
@en
Mitofusin2 mutations disrupt a ...... and promote axon degeneration
@nl
P2093
P2860
P3181
P1476
Mitofusin2 mutations disrupt a ...... and promote axon degeneration
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P2093
Albert L Misko
Elizabeth Tuck
Robert H Baloh
P2860
P304
P3181
P356
10.1523/JNEUROSCI.6338-11.2012
P407
P577
2012-03-01T00:00:00Z