Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN
about
Redox Signaling in Diabetic Nephropathy: Hypertrophy versus Death Choices in Mesangial Cells and PodocytesCellular and Molecular Mechanisms of Chronic Kidney Disease with Diabetes Mellitus and Cardiovascular Diseases as Its ComorbiditiesMini-review: emerging roles of microRNAs in the pathophysiology of renal diseasesPI3K/PTEN signaling in angiogenesis and tumorigenesisTGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansionIdiopathic pulmonary fibrosis: aberrant recapitulation of developmental programs?Optical imaging of cell mass and growth dynamics.Aging-associated dysfunction of Akt/protein kinase B: S-nitrosylation and acetaminophen intervention.PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in miceUpregulated DJ-1 promotes renal tubular EMT by suppressing cytoplasmic PTEN expression and Akt activation.Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells.microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasionIncrease in GLUT1 in smooth muscle alters vascular contractility and increases inflammation in response to vascular injuryHigh glucose forces a positive feedback loop connecting Akt kinase and FoxO1 transcription factor to activate mTORC1 kinase for mesangial cell hypertrophy and matrix protein expression.Urinary microRNA profiling in the nephropathy of type 1 diabetes.Regulation of mRNA translation in renal physiology and disease.Repression of let-7 by transforming growth factor-β1-induced Lin28 upregulates collagen expression in glomerular mesangial cells under diabetic conditions.Activation of glycogen synthase kinase 3β ameliorates diabetes-induced kidney injury.20-HETE and EETs in diabetic nephropathy: a novel mechanistic pathwayMicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes.TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen I (α2) gene expression.Loss of PTEN promotes podocyte cytoskeletal rearrangement, aggravating diabetic nephropathyHigh glucose enhances microRNA-26a to activate mTORC1 for mesangial cell hypertrophy and matrix protein expression.Reduced beta 2 glycoprotein I improves diabetic nephropathy via inhibiting TGF-β1-p38 MAPK pathwayReduced beta 2 glycoprotein I improve diabetic nephropathy via inhibiting TGF-β1-p38 MAPK pathwayLoss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responsesMicroRNAs and the glomerulusA microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cellsKidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cellsMicroRNA circuits in transforming growth factor-β actions and diabetic nephropathy.MicroRNAs in diabetic nephropathy: functions, biomarkers, and therapeutic targets.Association of PTEN gene polymorphisms with liver cancer risk.Transforming growth factor β integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy.Hydrophobic motif site-phosphorylated protein kinase CβII between mTORC2 and Akt regulates high glucose-induced mesangial cell hypertrophy.Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expressionHistone Lysine Methylation in TGF-β1 Mediated p21 Gene Expression in Rat Mesangial Cells.Urine miRNAs: potential biomarkers for monitoring progression of early stages of diabetic nephropathy.TGF-β induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy.Programmed cell death 4 (PDCD4): a novel player in ethanol-mediated suppression of protein translation in primary cortical neurons and developing cerebral cortex.Requirement for active glycogen synthase kinase-3β in TGF-β1 upregulation of connective tissue growth factor (CCN2/CTGF) levels in human gingival fibroblasts.
P2860
Q26778527-FB52E4C3-70F6-400A-BE5D-88EE94B62D47Q26798487-C99C337B-C3AB-4B14-BF2F-B0315CEEC7FFQ28354033-11B63043-BB14-464B-9CD8-FEF9194964F1Q28383083-2464A4C8-B7FC-479E-9815-DC3CC94ACA6EQ28975741-C54DFBC3-CCC9-4D1B-8EBA-F87056BBDAF8Q30841647-4BF1C80A-2CC1-4A8C-A090-0E7343D0B861Q33344710-5330DCAA-92EA-4480-B169-26035CA75D26Q33488518-C422EA83-F246-442B-9F0F-7562EFE65417Q33608760-16C70829-B621-413E-ABCD-5BF3B426AD0BQ33984914-6957BD5E-8D7B-4C7A-95C5-D91C3919579CQ34232095-86DB79D3-BC71-4821-B98C-0FC5D39B6CABQ34299534-8BEA19E2-297E-4AC4-8AAF-6B2ADFD4CF62Q34459819-B1AC1330-53ED-4DD1-B966-B541CBEB198AQ34552665-37531CBF-661A-49DF-9AD0-8F693E7FCDC7Q34566051-9A0D8EE3-BD65-49BA-95BA-63FE56A01E38Q34609025-57973EA6-9E5E-41A6-9B4A-4AEA94716CABQ34726882-1775879E-49EA-4B98-9A80-5DCE5AF5D539Q34737936-50C029FB-1974-4BAE-9A5A-F2BA2C25EF08Q34924935-6856DF88-0FB6-4DBB-9F3A-914227D12B57Q35110986-2CBB1AA6-E01F-4740-9347-4716BFE8B7B3Q35354812-9C6C12B1-8DB1-400B-B0E5-49F548FC7823Q35434381-A291623B-60AB-46CF-9A64-01B7C36D9207Q35625038-A32A0729-7B70-4CAA-9E4E-C0A8AEDE6301Q35631986-C82E4C1B-E38F-4FB3-8BE7-0886FD804BBDQ35870605-23D5DE43-B2E7-406A-815B-68437310BC48Q35875454-98E621FC-F187-419C-8DD2-7FFDD2B819D5Q35907222-CC2B8A0B-423D-4AD2-931F-DC68A9581BE6Q35915947-D7A6B46C-9F66-4072-9723-58657F778EB8Q35916771-6121A108-4B13-4E43-8C46-131104442943Q36124250-8D4D032D-D5C3-4D29-B832-F63F2CE0BE47Q36166755-9B23FCA1-450C-4FB1-A1E1-57E82DF50703Q36464903-4D92A2FD-BC2C-41F5-8848-AE80E4B331E4Q36685205-5C303E65-CF93-42E6-A7A9-928ACE808EE3Q36775718-4088D6DD-381C-4758-B2AF-BCBFB4B15969Q36855830-6837C657-3991-4697-BF4D-B71AA1FD118CQ36924772-527AB078-60F4-499C-ABE9-CD4ADE7267B6Q36997188-F361DFB3-FA6E-47BA-954E-9CBB3DE5E080Q37045293-FA948A60-028D-44AF-B891-82FCA5B4BD65Q37047806-A6EBE586-7264-4CDB-AE78-57C9269B2A7DQ37142420-09D5FBED-767C-4966-AC6D-3065CE2437EB
P2860
Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN
description
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Juli 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/07/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/07/01)
@nl
наукова стаття, опублікована в липні 2006
@uk
مقالة علمية (نشرت في يوليو 2006)
@ar
name
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@ast
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@en
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@nl
type
label
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@ast
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@en
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@nl
prefLabel
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@ast
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@en
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@nl
P2093
P3181
P356
P1433
P1476
Mesangial cell hypertrophy by ...... n of the tumor suppressor PTEN
@en
P2093
Balachandar Venkatesan
Falguni Das
Goutam Ghosh Choudhury
P304
P3181
P356
10.2337/DB05-1326
P407
P577
2006-07-01T00:00:00Z