Ca(2+)-dependent protein kinase C isoforms are critical to estradiol 17beta-D-glucuronide-induced cholestasis in the rat
about
Role of protein kinase C isoforms in bile formation and cholestasisRapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization.Enhancement of interaction of BSEP and HAX-1 on the canalicular membrane of hepatocytes in a mouse model of cholesterol cholelithiasis.Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression.The bile salt export pump: clinical and experimental aspects of genetic and acquired cholestatic liver diseaseERK1/2 and p38 MAPKs are complementarily involved in estradiol 17ß-D-glucuronide-induced cholestasis: crosstalk with cPKC and PI3K.Sequential activation of classic PKC and estrogen receptor α is involved in estradiol 17ß-D-glucuronide-induced cholestasis.Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor.A C-terminal tyrosine-based motif in the bile salt export pump directs clathrin-dependent endocytosis.Canalicular membrane MRP2/ABCC2 internalization is determined by Ezrin Thr567 phosphorylation in human obstructive cholestasisTaurolithocholate-induced MRP2 retrieval involves MARCKS phosphorylation by protein kinase Cϵ in HUH-NTCP Cells.Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations.Dynamic localization of hepatocellular transporters in health and disease.Altered functions and expressions of drug transporters in liver, kidney and intestine in disorders of local and remote organs: possible role of oxidative stress in the pathogenesis.Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system.Autoimmune BSEP disease: disease recurrence after liver transplantation for progressive familial intrahepatic cholestasis.Nonalcoholic Steatohepatitis Modulates Membrane Protein Retrieval and Insertion Processes.A dileucine motif is involved in plasma membrane expression and endocytosis of rat sodium taurocholate cotransporting polypeptide (Ntcp).EGFR participates downstream of ERα in estradiol-17β-D-glucuronide-induced impairment of Abcc2 function in isolated rat hepatocyte couplets.Mechanism of inhibition of taurolithocholate-induced retrieval of plasma membrane MRP2 by cyclic AMP and tauroursodeoxycholate.Activation of insulin-like growth factor 1 receptor participates downstream of GPR30 in estradiol-17β-D-glucuronide-induced cholestasis in rats.Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-D-glucuronide in rat intestine and Caco-2 cells.Why is the female population more susceptible to cholestasis-induced liver injury-Could it be long noncoding RNA H19?Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis.Mitogen-activated protein kinases are involved in hepatocanalicular dysfunction and cholestasis induced by oxidative stress.G-protein-coupled receptor 30/adenylyl cyclase/protein kinase A pathway is involved in estradiol 17ß-D-glucuronide-induced cholestasis.Hormonal modulation of hepatic cAMP prevents estradiol 17β-D-glucuronide-induced cholestasis in perfused rat liver.Sandwich-cultured rat hepatocytes as an in vitro model to study canalicular transport alterations in cholestasis
P2860
Q27001101-66851FD9-5215-496E-BF37-670AB63FF05FQ30494155-F27415C1-5839-4A0D-9EFE-8F597059AAA7Q33583024-57D6A9F9-7686-400E-85A5-78EA14C72A1FQ33624522-5C6CCEDC-4F35-4A9D-966F-D6DA0966CACAQ34432666-F799B30D-880D-4D3F-8A86-3258AEA25644Q34482125-98FD9D2D-87E2-4882-91E1-C8E794423C7AQ34500649-1AFBD66E-EDCB-4CE9-9076-5608234E44C7Q35564302-D313343F-2A3E-46F3-9239-0B7B4EF676CDQ35871064-0FBAD7AA-E992-4790-94F9-8604228CEBD5Q36390520-3E5A20F1-767D-48E5-A3FE-ECAE6CA3D848Q36927112-6172BA5C-5E90-46CD-B5A6-F4743475E50CQ37200971-3A92F117-768C-45B9-98D4-CBB9A64A0922Q37341910-AC52247A-091D-4776-A318-F76CA5C31BE2Q37556541-9680DCA5-A27B-42D6-8110-D181881FB28AQ37619727-BCD4B1D1-0FA3-4D8E-858D-5FBF49143287Q38262461-3E6EBCB5-F1DC-4D08-818D-AEBA16E80997Q39413692-FBFB97E2-C198-4C46-8D66-FB050C7E8915Q42248702-D46E3DFC-2FE9-43D2-B89A-150E0D389AA6Q42702172-364C6DC4-D915-4E92-90E0-A1B88CB870C7Q47396176-31264555-79E7-4553-9E96-D91075B12221Q47579718-A2015968-E24B-4F9A-A239-BA14F2D01953Q47625097-B0B4A7B1-1500-4E63-93EB-846E02BB4485Q47762522-D5F90482-8BC1-4C86-93A5-34BA61658E6AQ48228323-B7020B4A-35ED-4787-9771-44D931F57699Q51287971-3AB7DFFA-C86F-4CF7-AE28-2E60F311CDC3Q54403883-AB976569-5B27-47F7-BF41-409BDDF3818EQ54452710-5551229A-04B4-45E3-8A12-C5288C1DD228Q57144445-C6A0ED0D-F696-4B88-9D8D-E021FB192DE9
P2860
Ca(2+)-dependent protein kinase C isoforms are critical to estradiol 17beta-D-glucuronide-induced cholestasis in the rat
description
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Dezember 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/12/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/12/01)
@nl
наукова стаття, опублікована в грудні 2008
@uk
مقالة علمية (نشرت في ديسمبر 2008)
@ar
name
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@ast
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@en
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@nl
type
label
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@ast
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@en
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@nl
prefLabel
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@ast
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@en
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@nl
P2093
P2860
P356
P1433
P1476
Ca(2+)-dependent protein kinas ...... induced cholestasis in the rat
@en
P2093
Aldo D Mottino
Andrés E Zucchetti
Marcelo G Roma
María Laura Ruiz
P2860
P304
P356
10.1002/HEP.22532
P407
P577
2008-12-01T00:00:00Z