Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity
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Differences in muscle transcriptome among pigs phenotypically extreme for fatty acid compositionDecoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans.Skeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulationThe application of transcriptomic data in the authentication of beef derived from contrasting production systems.Piecing together the puzzle of perilipin proteins and skeletal muscle lipolysis.Muscle Lipid Metabolism: Role of Lipid Droplets and PerilipinsCellular localization and associations of the major lipolytic proteins in human skeletal muscle at rest and during exercise.Mitochondrial and cellular mechanisms for managing lipid excess.PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle.Higher PLIN5 but not PLIN3 content in isolated skeletal muscle mitochondria following acute in vivo contraction in rat hindlimb.Arsenic exposure in early pregnancy alters genome-wide DNA methylation in cord blood, particularly in boys.Skeletal muscle perilipin 3 and coatomer proteins are increased following exercise and are associated with fat oxidationPerilipin 5-Driven Lipid Droplet Accumulation in Skeletal Muscle Stimulates the Expression of Fibroblast Growth Factor 21Perilipin 5, a lipid droplet protein adapted to mitochondrial energy utilization.Liver Perilipin 5 Expression Worsens Hepatosteatosis But Not Insulin Resistance in High Fat-Fed Mice.Perilipin 3 Differentially Regulates Skeletal Muscle Lipid Oxidation in Active, Sedentary, and Type 2 Diabetic MalesDocosahexaenoic acid-supplementation prior to fasting prevents muscle atrophy in mice.Adipose tissue depot specific differences of PLIN protein content in endurance trained ratsSkeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity.Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial functionOn the performance of tests for the detection of signatures of selection: a case study with the Spanish autochthonous beef cattle populations.Perilipin 5 fine-tunes lipid oxidation to metabolic demand and protects against lipotoxicity in skeletal muscle.Can resveratrol help to maintain metabolic health?Targeting fatty acid metabolism to improve glucose metabolism.Combatting type 2 diabetes by turning up the heat.Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South AsiansReduced incorporation of fatty acids into triacylglycerol in myotubes from obese individuals with type 2 diabetes.Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes.Use of fluorescence microscopy to probe intracellular lipolysis.Perilipin 5 mediated lipid droplet remodelling revealed by coherent Raman imaging.Dissociation of intramyocellular lipid storage and insulin resistance in trained athletes and type 2 diabetes patients; involvement of perilipin 5?Effect of acute physiological free fatty acid elevation in the context of hyperinsulinemia on fiber type-specific IMCL accumulation.The perilipin family of lipid droplet proteins: Gatekeepers of intracellular lipolysis.Lipid droplet remodelling and reduced muscle ceramides following sprint interval and moderate-intensity continuous exercise training in obese males.The athlete's paradOXpat.Training alters the distribution of perilipin proteins in muscle following acute free fatty acid exposure.Changes in mitochondrial perilipin 3 and perilipin 5 protein content in rat skeletal muscle following endurance training and acute stimulated contraction.Perilipin 5 is dispensable for normal substrate metabolism and in the adaptation of skeletal muscle to exercise training.Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradoxTranscriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock
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P2860
Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity
description
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2013
@ast
im April 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/04/01)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/04/01)
@nl
наукова стаття, опублікована у квітні 2013
@uk
مقالة علمية (نشرت في أبريل 2013)
@ar
name
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@ast
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@en
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@nl
type
label
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@ast
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@en
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@nl
prefLabel
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@ast
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@en
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@nl
P2093
P50
P3181
P1476
Overexpression of PLIN5 in ske ...... mpromising insulin sensitivity
@en
P2093
J A Jorgensen
L M Sparks
M K C Hesselink
P304
P3181
P356
10.1016/J.BBALIP.2013.01.007
P407
P577
2013-01-22T00:00:00Z