Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
about
A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic aciniRab27a and Rab27b control different steps of the exosome secretion pathwayCa²⁺-regulated secretory granule exocytosis in pancreatic and parotid acinar cellsRegulation of vesicular trafficking and leukocyte function by Rab27 GTPases and their effectorsDirect imaging of RAB27B-enriched secretory vesicle biogenesis in lacrimal acinar cells reveals origins on a nascent vesicle budding siteMyosin Vc is a molecular motor that functions in secretory granule traffickingRab27b regulates exocytosis of secretory vesicles in acinar epithelial cells from the lacrimal gland.Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome.Live pancreatic acinar imaging of exocytosis using syncollin-pHluorin.Rab27a and Rab27b regulate neutrophil azurophilic granule exocytosis and NADPH oxidase activity by independent mechanisms.Regulation of synaptic transmission by RAB-3 and RAB-27 in Caenorhabditis elegans.A Rab11a-enriched subapical membrane compartment regulates a cytoskeleton-dependent transcytotic pathway in secretory epithelial cells of the lacrimal gland.Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion.Rab27b regulates number and secretion of platelet dense granules.Differential expression of Rab27A/B correlates with clinical outcome in hepatocellular carcinoma.Rab27b is expressed in a wide range of exocytic cells and involved in the delivery of secretory granules near the plasma membrane.Rab27b regulates mast cell granule dynamics and secretion.Genetic deletion of Rab27B in pancreatic acinar cells affects granules size and has inhibitory effects on amylase secretion.The class V myosin motor, myosin 5c, localizes to mature secretory vesicles and facilitates exocytosis in lacrimal aciniGenome-wide association analysis identifies three new susceptibility loci for childhood body mass indexSequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cellsPolymeric immunoglobulin receptor traffics through two distinct apically targeted pathways in primary lacrimal gland acinar cells.Proteomic analysis of pancreatic zymogen granules: identification of new granule proteins.EPI64B acts as a GTPase-activating protein for Rab27B in pancreatic acinar cellsSmall G proteins as key regulators of pancreatic digestive enzyme secretion.Fusion of lysosomes with secretory organelles leads to uncontrolled exocytosis in the lysosomal storage disease mucolipidosis type IV.Proteomic analysis of zymogen granules.Interplay between Rab27a effectors in pancreatic β-cells.Rab3D regulates amylase levels, not agonist-induced amylase release, in AR42J cells.Rab8 is involved in zymogen granule formation in pancreatic acinar AR42J cells.Expression of pro-Muclin in pancreatic AR42J cells induces functional regulated secretory granules.Rap1 activation plays a regulatory role in pancreatic amylase secretion.Disruption of Small GTPase Rab7 Exacerbates the Severity of Acute Pancreatitis in Experimental Mouse Models.Molecular architecture of mouse and human pancreatic zymogen granules: protein components and their copy numbers.Functional implications of Rab27 GTPases in Cancer
P2860
Q24303465-05E1A9F3-9782-4200-9A9A-3DB08B4C83A8Q24336455-52E3F7CE-DBA0-4666-BDCD-D4FCA629C13BQ26825529-C43C15B0-9B4A-47B8-9B3C-645F75E0530EQ27012658-793215B7-7347-46A1-9DB8-159822DEF734Q27308870-E6AC5005-2908-4834-BE88-084656EBC5B4Q28117478-477052D1-D933-4C44-B576-470ADAA83427Q30503398-A0558156-B53E-4AEA-A615-A170513FACA8Q30781352-D594659D-24DF-43A8-A74F-872815140D6BQ33816626-AA312F93-B371-466C-90AF-7ED737E0D703Q34118192-3F78969A-3122-4505-93D8-F1330841D409Q34661691-7736AF30-C5BE-4BA4-A656-1BE6648A980BQ35389040-A81FD9E6-DFEA-4137-B110-D48796CC0772Q35624339-17CE1F17-074F-4C5F-9D00-6839D0D4A1F9Q35696422-7F2CB57D-50EF-4C29-814A-23D3911068DEQ35904317-72E0E87E-04FB-4EC7-BA31-7496805569FBQ36095761-D2B71114-498E-4545-9653-963B6BE3629BQ36117012-9BEAA284-94F6-4617-AC22-70D7F7C8E9AAQ36743856-3FEE6FF8-B8EC-4ABA-8AC1-F3524F71FB2DQ36805329-81EF393D-2CC1-42BE-89D0-9382A69823E4Q36861322-1DD57151-4D65-4BDF-8B41-A948A3BF4CA4Q36896310-81A93E37-C310-4F18-86A8-B83211E3E367Q36943322-AC139D56-5E85-4A3B-B853-9CC0E470F4B7Q36969936-578ACC0B-85A5-41A4-961B-F10E7094BA67Q37000544-F9D462BC-CA48-4683-9709-017C8F8E0B13Q37138723-827DB393-3E4C-471C-AA6D-1E38D96DC857Q37623318-AE592EBA-A0B0-4952-8A2F-EECE39939CD6Q37802876-70EBDE15-90F5-4AC4-B1C5-BB06501AF79BQ38432549-9197379A-8F22-448C-AD06-003CCC986557Q39389692-C69CC4B4-2A23-4BA0-A347-59EC570AD6B4Q39998912-B07B30C7-2A66-482E-8FFE-40A43373C6B4Q40403521-7CA03CD4-C8E0-4EB1-BFD0-A82DAB58E6C2Q41856499-74CA513C-6CF8-41FB-9931-D34126B71F5EQ42220118-635E6BF9-00A0-4E74-A3F0-B7C1D375BA37Q54961165-F38C20A4-81D9-433F-954A-0E0A35C61F51Q58799369-0E2E08CE-18AA-4F86-9CE1-FE2DAD4BEFEB
P2860
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
description
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Oktober 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/10/29)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/10/29)
@nl
наукова стаття, опублікована в жовтні 2004
@uk
مقالة علمية (نشرت في 29-10-2004)
@ar
name
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@ast
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@en
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@nl
type
label
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@ast
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@en
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@nl
prefLabel
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@ast
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@en
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@nl
P2093
P3181
P1476
Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis
@en
P2093
Chenwei Li
Stephen A. Ernst
Tetsuro Izumi
Xuequn Chen
P304
P3181
P356
10.1016/J.BBRC.2004.08.212
P407
P577
2004-10-29T00:00:00Z