Androgens repress the expression of the angiogenesis inhibitor thrombospondin-1 in normal and neoplastic prostate
about
Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumorsCalpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of diseaseSIRNA-directed in vivo silencing of androgen receptor inhibits the growth of castration-resistant prostate carcinomas.Androgenic dependence of exophytic tumor growth in a transgenic mouse model of bladder cancer: a role for thrombospondin-1.Androgen receptor targets NFkappaB and TSP1 to suppress prostate tumor growth in vivo.The long and winding road for the development of tasquinimod as an oral second-generation quinoline-3-carboxamide antiangiogenic drug for the treatment of prostate cancer.Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumorsAging-related alterations in the extracellular matrix modulate the microenvironment and influence tumor progression.Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice.Androgen regulation of gene expression in human meibomian gland and conjunctival epithelial cells.Extracellular influences on tumour angiogenesis in the aged host.Sex hormones and mucosal wound healing.Gene Expression Profiling Reveals Regulation of ERK Phosphorylation by Androgen-Induced Tumor Suppressor U19/EAF2 in the Mouse Prostate.Beta1 integrin cytoplasmic variants differentially regulate expression of the antiangiogenic extracellular matrix protein thrombospondin 1.Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells.A review of tasquinimod in the treatment of advanced prostate cancer.Thrombospondin-1 in urological cancer: pathological role, clinical significance, and therapeutic prospects.Mechanisms of action of tasquinimod on the tumour microenvironment.Thrombospondin-1 regulates the normal prostate in vivo through angiogenesis and TGF-beta activation.Tasquinimod prevents the angiogenic rebound induced by fractionated radiation resulting in an enhanced therapeutic response of prostate cancer xenografts.Pathological significance and prognostic role of microvessel density, evaluated using CD31, CD34, and CD105 in prostate cancer patients after radical prostatectomy with neoadjuvant therapy.The role of the tumor microenvironment in regulating angiogenesis.The PCAT3/PCAT9-miR-203-SNAI2 axis functions as a key mediator for prostate tumor growth and progression.Fatty Acids and Calcium Regulation in Prostate Cancer.
P2860
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P2860
Androgens repress the expression of the angiogenesis inhibitor thrombospondin-1 in normal and neoplastic prostate
description
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artikull shkencor
@sq
artículu científicu espublizáu en 2005
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im Januar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
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wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2005
@uk
مقالة علمية (نشرت عام 2005)
@ar
name
Androgens repress the expressi ...... normal and neoplastic prostate
@ast
Androgens repress the expressi ...... normal and neoplastic prostate
@en
Androgens repress the expressi ...... normal and neoplastic prostate
@nl
type
label
Androgens repress the expressi ...... normal and neoplastic prostate
@ast
Androgens repress the expressi ...... normal and neoplastic prostate
@en
Androgens repress the expressi ...... normal and neoplastic prostate
@nl
prefLabel
Androgens repress the expressi ...... normal and neoplastic prostate
@ast
Androgens repress the expressi ...... normal and neoplastic prostate
@en
Androgens repress the expressi ...... normal and neoplastic prostate
@nl
P2093
P1433
P1476
Androgens repress the expressi ...... normal and neoplastic prostate
@en
P2093
Armelle Degeorges
Aurélie Courtin
Carole Merle
Claire Marie Serre
Florence Cabon
Julien Guglielmi
Philippe Clézardin
Pierick Fournier
Raymonde Bouvier
P304
P407
P577
2005-01-01T00:00:00Z