Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets
about
Cyclic AMP dynamics in the pancreatic β-cellAdenylyl cyclase 8 is central to glucagon-like peptide 1 signalling and effects of chronically elevated glucose in rat and human pancreatic beta cellsPharmacokinetic/Pharmacodynamic Modeling of the PDE4 Inhibitor TAK-648 in Type 2 Diabetes: Early Translational Approaches for Human Dose PredictionSphingosine kinase 1-interacting protein is a novel regulator of glucose-stimulated insulin secretionExpression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets.Repurposing cAMP-modulating medications to promote β-cell replication.Resveratrol and curcumin enhance pancreatic β-cell function by inhibiting phosphodiesterase activity.Whole genome SNP genotyping and exome sequencing reveal novel genetic variants and putative causative genes in congenital hyperinsulinism.Alterations in cyclic nucleotide phosphodiesterase activities in omental and subcutaneous adipose tissues in human obesity.Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells.RNA-Seq Analysis of Abdominal Fat in Genetically Fat and Lean Chickens Highlights a Divergence in Expression of Genes Controlling Adiposity, Hemostasis, and Lipid MetabolismResveratrol as a calorie restriction mimetic: therapeutic implications.Chronic obstructive pulmonary disease: an update of treatment related to frequently associated comorbidities.Monomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets.PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets.Clinical and molecular genetics of the phosphodiesterases (PDEs).Optogenetic regulation of insulin secretion in pancreatic β-cells.Differential metabolic effects of novel cilostamide analogs, methyl carbostiryl derivatives, on mouse and hyperglycemic rat.Apelin inhibits insulin secretion in pancreatic beta-cells by activation of PI3-kinase-phosphodiesterase 3B.Roflumilast Ameliorates Airway Hyperresponsiveness Caused by Diet-Induced Obesity in a Murine Model.
P2860
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P2860
Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets
description
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Oktober 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/10/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/10/01)
@nl
наукова стаття, опублікована в жовтні 2008
@uk
مقالة علمية (نشرت في أكتوبر 2008)
@ar
name
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@ast
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@en
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@nl
type
label
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@ast
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@en
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@nl
prefLabel
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@ast
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@en
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@nl
P2093
P3181
P1476
Phosphodiesterase 3 and 4 comp ...... (832/13) cells and rat islets
@en
P2093
Andrew Howard
Chris Thompson
Deena Waddleton
Joseph A. Mancini
Michael Wu
Nancy Thornberry
Weizhen Wu
Yun-Ping Zhou
P304
P3181
P356
10.1016/J.BCP.2008.07.025
P407
P577
2008-10-01T00:00:00Z