Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein
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Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytesZinc-Independent Folate Biosynthesis: Genetic, Biochemical, and Structural Investigations Reveal New Metal Dependence for GTP Cyclohydrolase IBPet-1 Controls Tetrahydrobiopterin Pathway and Slc22a3 Transporter Genes in Serotonin NeuronsUnusual arginine formations in protein function and assembly: rings, strings, and stacks.Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase ITetrahydrobiopterin, superoxide, and vascular dysfunction.A novel high-throughput screening assay for discovery of molecules that increase cellular tetrahydrobiopterin.Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers.Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin.The N-terminal peptide of mammalian GTP cyclohydrolase I is an autoinhibitory control element and contributes to binding the allosteric regulatory protein GFRP.Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.Cuticle integrity and biogenic amine synthesis in Caenorhabditis elegans require the cofactor tetrahydrobiopterin (BH4).Novel strategies to ameliorate radiation injury: a possible role for tetrahydrobiopterinValidating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approachesBiochemical characterization of the tetrahydrobiopterin synthesis pathway in the oleaginous fungus Mortierella alpina.Direct evidence for the adaptive role of copy number variation on antifolate susceptibility in Plasmodium falciparum.Cytokines and lipopolysaccharides induce inducible nitric oxide synthase but not enzyme activity in adult rat cardiomyocytes.Mechanism and catalytic strategy of the prokaryotic-specific GTP cyclohydrolase-IB.Interaction of human GTP cyclohydrolase I with its splice variants.Dopa-responsive dystonia in a ten-year-old girl.A typical N-terminal extensions confer novel regulatory properties on GTP cyclohydrolase isoforms in Drosophila melanogaster.Structures and reaction mechanisms of GTP cyclohydrolases.
P2860
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P2860
Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/03)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/03)
@nl
наукова стаття, опублікована в грудні 2004
@uk
name
Structural basis of biopterin- ...... ts feedback regulatory protein
@ast
Structural basis of biopterin- ...... ts feedback regulatory protein
@en
Structural basis of biopterin- ...... ts feedback regulatory protein
@nl
type
label
Structural basis of biopterin- ...... ts feedback regulatory protein
@ast
Structural basis of biopterin- ...... ts feedback regulatory protein
@en
Structural basis of biopterin- ...... ts feedback regulatory protein
@nl
prefLabel
Structural basis of biopterin- ...... ts feedback regulatory protein
@ast
Structural basis of biopterin- ...... ts feedback regulatory protein
@en
Structural basis of biopterin- ...... ts feedback regulatory protein
@nl
P2093
P2860
P356
P1476
Structural basis of biopterin- ...... ts feedback regulatory protein
@en
P2093
Kazuyuki Hatakeyama
Kengo Okada
Nobuo Maita
Toshio Hakoshima
P2860
P304
51534–51540
P356
10.1074/JBC.M409440200
P407
P577
2004-12-03T00:00:00Z