Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation - Wikidata - wikimedia - TriplyDB

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

http://www.wikidata.org/entity/Q28570513

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Posttranslational control of HuR function RNA-binding proteins and microRNAs in gastrointestinal epithelial homeostasis and diseases Regulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1 Post-transcriptional regulation of Wnt co-receptor LRP6 and RNA-binding protein HuR by miR-29b in intestinal epithelial cells miR-29b represses intestinal mucosal growth by inhibiting translation of cyclin-dependent kinase 2 Polyamines inhibit the assembly of stress granules in normal intestinal epithelial cells regulating apoptosis Activation of Wnt3a signaling stimulates intestinal epithelial repair by promoting c-Myc-regulated gene expression Induced ATF-2 represses CDK4 transcription through dimerization with JunD inhibiting intestinal epithelial cell growth after polyamine depletion Polyamines regulate the stability of JunD mRNA by modulating the competitive binding of its 3' untranslated region to HuR and AUF1 Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function Cytoplasmic accumulation of the RNA-binding protein HuR stabilizes the ornithine decarboxylase transcript in a murine nonmelanoma skin cancer model.Polyamines and Gut Mucosal Homeostasis.miR-503 represses CUG-binding protein 1 translation by recruiting CUGBP1 mRNA to processing bodies.RNA-binding protein HuR promotes growth of small intestinal mucosa by activating the Wnt signaling pathway.Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis.ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation.Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal.AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells.The RNA-binding protein RNPC1 stabilizes the mRNA encoding the RNA-binding protein HuR and cooperates with HuR to suppress cell proliferation Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca²+ signaling by differentially modulating STIM1 and STIM2.Phosphoregulation of the RNA-binding protein Hu antigen R (HuR) by Cdk5 affects centrosome function.Dephosphorylation of HuR protein during alphavirus infection is associated with HuR relocalization to the cytoplasm miR-17-92 fine-tunes MYC expression and function to ensure optimal B cell lymphoma growth.Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function.Overexpression of miR-214-3p in esophageal squamous cancer cells enhances sensitivity to cisplatin by targeting survivin directly and indirectly through CUG-BP1.Long noncoding RNA SPRY4-IT1 regulates intestinal epithelial barrier function by modulating the expression levels of tight junction proteins.A role for polyamine regulators in ESC self-renewal H19 Long Noncoding RNA Regulates Intestinal Epithelial Barrier Function via MicroRNA 675 by Interacting with RNA-Binding Protein HuR.Current status of the polyamine research field ATP13A3 and caveolin-1 as potential biomarkers for difluoromethylornithine-based therapies in pancreatic cancers miR-195 competes with HuR to modulate stim1 mRNA stability and regulate cell migration Stabilization of XIAP mRNA through the RNA binding protein HuR regulated by cellular polyamines.Anthrax lethal toxin inhibits translation of hypoxia-inducible factor 1α and causes decreased tolerance to hypoxic stress Inhibition of Smurf2 translation by miR-322/503 modulates TGF-β/Smad2 signaling and intestinal epithelial homeostasis.Turnover of AU-rich-containing mRNAs during stress: a matter of survival.HuR's role in gemcitabine efficacy: an exception or opportunity?Disruption of prostate epithelial differentiation pathways and prostate cancer development.

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Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

http://www.wikidata.org/entity/Q28570513

description

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2009

@ast

im Dezember 2009 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2009/12/01)

@sk

vědecký článek publikovaný v roce 2009

@cs

wetenschappelijk artikel (gepubliceerd op 2009/12/01)

@nl

наукова стаття, опублікована в грудні 2009

@uk

مقالة علمية (نشرت في ديسمبر 2009)

@ar

name

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@ast

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@en

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@nl

type

label

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@ast

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@en

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@nl

prefLabel

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@ast

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@en

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@nl

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P356

MBC.E09-07-0550

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Molecular Biology of the Cell

P1476

Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation

@en

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Douglas J. Turner

http://www.w3.org/2001/XMLSchema#string

Jaladanki N. Rao

http://www.w3.org/2001/XMLSchema#string

Jian-Ying Wang

http://www.w3.org/2001/XMLSchema#string

Lan Liu

http://www.w3.org/2001/XMLSchema#string

Lan Xiao

http://www.w3.org/2001/XMLSchema#string

Peng-Yuan Wang

http://www.w3.org/2001/XMLSchema#string

Tongtong Zou

http://www.w3.org/2001/XMLSchema#string

P2860

Control of mRNA decay by heat shock-ubiquitin-proteasome pathway

Phosphorylation of HuR by Chk2 regulates SIRT1 expression

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin

ARED: human AU-rich element-containing mRNA database reveals an unexpectedly diverse functional repertoire of encoded proteins

HuR recruits let-7/RISC to repress c-Myc expression

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2

Relief of microRNA-mediated translational repression in human cells subjected to stress

A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery

A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

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4885–4898

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scholarly article

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2251746

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P356

10.1091/MBC.E09-07-0550

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23

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20

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P577

2009-12-01T00:00:00Z

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19812253

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phosphorylation

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2785732

http://www.w3.org/2001/XMLSchema#string