P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: implications for age-associated vascular dysfunction
about
The endothelium abridges insulin resistance to premature agingMitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular DysfunctionNitric oxide, oxidative stress, and p66Shc interplay in diabetic endothelial dysfunctionAge-related changes in brain support cells: Implications for stroke severityTranscriptional repression of Kruppel like factor-2 by the adaptor protein p66shc.Effects of aging on angiogenesis.Mechanisms of vascular aging: new perspectives.Dual role of endothelial nitric oxide synthase in oxidized LDL-induced, p66Shc-mediated oxidative stress in cultured human endothelial cells.Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc.Tat-Mediated p66shc Transduction Decreased Phosphorylation of Endothelial Nitric Oxide Synthase in Endothelial Cells.Epigenetic upregulation of p66shc mediates low-density lipoprotein cholesterol-induced endothelial cell dysfunctionp66shc negatively regulates insulin-like growth factor I signal transduction via inhibition of p52shc binding to Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 leading to impaired growth factor receptor-bound protein-2 memRole of mitochondrial dysfunction and altered autophagy in cardiovascular aging and disease: from mechanisms to therapeutics.Anti-aging medicine: molecular basis for endothelial cell-targeted strategies - a mini-review.Mitochondria and aging in the vascular system.MicroRNA miR-27b rescues bone marrow-derived angiogenic cell function and accelerates wound healing in type 2 diabetes mellitus.New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases.p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes.Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction.p53 impairs endothelial function by transcriptionally repressing Kruppel-Like Factor 2.Arginase II: atherogenesis beyond enzyme activity.p66(Shc) has a pivotal function in impaired liver regeneration in aged mice by a redox-dependent mechanism.Alteration of p66shc is associated with endothelial dysfunction in the abdominal aortic coarctation of rats.Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium.The expression of p66shc in peripheral blood monocytes is increased in patients with coronary heart disease and correlated with endothelium-dependent vasodilatation.
P2860
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P2860
P66shc regulates endothelial NO production and endothelium-dependent vasorelaxation: implications for age-associated vascular dysfunction
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/01)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في ديسمبر 2005)
@ar
name
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@ast
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@en
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@nl
type
label
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@ast
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@en
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@nl
prefLabel
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@ast
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@en
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@nl
P2093
P1476
P66shc regulates endothelial N ...... ssociated vascular dysfunction
@en
P2093
Anthony R White
Artem Bugayenko
Azeb Haile
Dan E Berkowitz
Firdous A Khanday
Ilwola Mattagajasingh
Kenji Kasuno
Tohru Yamamori
P304
P356
10.1016/J.YJMCC.2005.09.003
P577
2005-10-19T00:00:00Z