Heat-shock protein 90 augments neuronal nitric oxide synthase activity by enhancing Ca2+/calmodulin binding
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Molecular mechanisms of neuronal nitric oxide synthase in cardiac function and pathophysiologyNitric oxide acts as a positive regulator to induce metamorphosis of the ascidian Herdmania momusThe Bcl-2 regulator FKBP38-calmodulin-Ca2+ is inhibited by Hsp90.Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) and nNOS.Dose dependent effects of reactive oxygen and nitrogen species on the function of neuronal nitric oxide synthase.Structural and mechanistic aspects of flavoproteins: electron transfer through the nitric oxide synthase flavoprotein domain.Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage.A model in which heat shock protein 90 targets protein-folding clefts: rationale for a new approach to neuroprotective treatment of protein folding diseasesObligatory role of heat shock protein 90 in iNOS induction.Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleftNitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component?Modulation of heme/substrate binding cleft of neuronal nitric-oxide synthase (nNOS) regulates binding of Hsp90 and Hsp70 proteins and nNOS ubiquitinationSerine 1179 Phosphorylation of Endothelial Nitric Oxide Synthase Increases Superoxide Generation and Alters Cofactor Regulation.Ubiquitination of neuronal nitric-oxide synthase in the calmodulin-binding site triggers proteasomal degradation of the protein.Identification of mouse brain proteins associated with isoform 3 of metallothionein.Subcellular targeting and trafficking of nitric oxide synthases.Stromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation.Induction of angiogenesis by heat shock protein 90 mediated by protein kinase Akt and endothelial nitric oxide synthaseEssential role of the 90-kilodalton heat shock protein in mediating nongenomic estrogen signaling in coronary artery smooth muscle.Dynamic cycling with Hsp90 stabilizes neuronal nitric oxide synthase through calmodulin-dependent inhibition of ubiquitination.Increased nitric oxide synthase activity and Hsp90 association in skeletal muscle following chronic exercise.Current concepts on the role of nitric oxide in portal hypertension.No-dependent signaling pathways in unloaded skeletal muscle.Vitamin C and Microvascular Dysfunction in Systemic Inflammation.Role of HSP-90 for increased nNOS-mediated vasodilation in mesenteric arteries in portal hypertension.Roles of 3-phosphoinositide-dependent kinase 1 in the regulation of endothelial nitric-oxide synthase phosphorylation and function by heat shock protein 90.hsp90 is required for heme binding and activation of apo-neuronal nitric-oxide synthase: geldanamycin-mediated oxidant generation is unrelated to any action of hsp90.Sodium nitrite exerts an antihypertensive effect and improves endothelial function through activation of eNOS in the SHR.Calmodulin-dependent and -independent activation of endothelial nitric-oxide synthase by heat shock protein 90.Identification of caveolin-1-interacting sites in neuronal nitric-oxide synthase. Molecular mechanism for inhibition of NO formation.Nitric oxide is not a negative regulator of metamorphic induction in the abalone Haliotis asininaA Novel Mechanism for Cross-Adaptation between Heat and Altitude Acclimation: The Role of Heat Shock Protein 90
P2860
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P2860
Heat-shock protein 90 augments neuronal nitric oxide synthase activity by enhancing Ca2+/calmodulin binding
description
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
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im April 2001 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2001/04/15)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/04/15)
@nl
наукова стаття, опублікована у квітні 2001
@uk
مقالة علمية (نشرت في 15-4-2001)
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name
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@ast
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@en
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@nl
type
label
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@ast
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@en
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@nl
prefLabel
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@ast
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@en
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@nl
P2093
P2860
P3181
P1433
P1476
Heat-shock protein 90 augments ...... ancing Ca2+/calmodulin binding
@en
P2093
P2860
P304
P3181
P356
10.1042/0264-6021:3550357
P407
P577
2001-04-15T00:00:00Z